Review Article

MicroRNAs in Neurotoxicity

Figure 2

Pathology of Alzheimer’s disease and miRNAs involved in its neurotoxicity. There is cooperative regulation of the proteins involved in Aβ-induced neurotoxicity with several miRNAs to fine-tune their expression. Abbreviations: APP: amyloid precursor protein; BACE1: β-secretase or β-site APP-cleaving enzyme; CDS: coding sequence; sAPPα: secretory APPα; UTR: untranslated region.
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