Prenatal and Postnatal Polycyclic Aromatic Hydrocarbon Exposure, Airway Hyperreactivity, and Beta-2 Adrenergic Receptor Function in Sensitized Mouse Offspring
Figure 4
AHR following postnatal PAH exposure in the presence and absence of procaterol (Proc). Newtonian resistance (H2O/s/mL) was normalized to value measured following PBS aerosol exposure. Total sample size, followed by sample size for mice that completed highest dose, is listed in parentheses. The PAH/OVA mice showed borderline greater airway resistance when compared to the normal air/OVA group at the 64 mg/mL dose ( value = 0.055, two-tailed -test). Clear improvement across experimental groups following administration of procaterol is not evident.
