Impairment of Hepatic and Renal Functions by 2,5-Hexanedione Is Accompanied by Oxidative Stress in Rats

Figure 4

Influence of 2,5-HD on liver morphology after treatment for 21 consecutive days in rats. Representative photomicrographs of liver samples of rats in control (a) and 0.25% 2,5-HD (b) appear normal whereas mild central venous congestion (green arrow) and cellular infiltration (black arrow) by neutrophils were identified in 0.5% 2,5-HD (c) and 1% 2,5-HD (d).

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