Prognostic Factors in Acute Methadone Toxicity: A 5-Year Study

Table 1

Comparison of demographic data and clinical findings between survivors and nonsurvivors.

		Outcome
		Survivors	Nonsurvivors
Demographic data	Age			0.01
	Sex
	Male	73.8%	85.7%	N/S
	Female	26.2%	14.3%
	Mode of toxicity
	Intentional	84.3%	82.1%	N/S
	Accidental	15.7%	17.9%
	Patient on MMT program
	Yes	43.1%	82.4%	0.002
	No	56.9%	17.6%
Clinical finding at ED	MTD formulation
	Tablet	56.5%	76%	N/S
	Syrup	43.5%	24%
	Ingested dose			N/S
	Duration between consumption and admission (hours)			N/S
	Loss of consciousness
	Confused	45.6%	35.7%	<0.001
	Sleepy	13.6%	17.9%
	Stuporous	3.4%	17.9%
	Comatose	1.7%	25%
	Pupil size in the first examination
	Miotic	61.2%	57.1%	N/S
	Mid-sized	35.4%	39.3%
	Dilated	3.4%	3.6%
	Pulse rate			N/S
	Respiratory rate			0.01
	Blood pressure (mmHg)
	Systolic			0.002
	Diastolic			0.01
	Naloxone therapy
	Yes	39.8%	35.7%	N/S
Findings during hospitalization	Endotracheal intubation	17.7%	96.4%	<0.001
	Mean duration of hospitalization (days)			0.005

N/S: statistically nonsignificant ().