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Journal of Toxicology
Volume 2016, Article ID 7934257, 8 pages
http://dx.doi.org/10.1155/2016/7934257
Research Article

Biomonitoring with Micronuclei Test in Buccal Cells of Female Farmers and Children Exposed to Pesticides of Maneadero Agricultural Valley, Baja California, Mexico

1Facultad de Ciencias, Universidad Autónoma de Baja California, 22800 Ensenada, BC, Mexico
2Centro de Investigación Científica y de Educación Superior de Ensenada, 22800 Ensenada, BC, Mexico
3Escuela de Ciencias de la Salud, Universidad Autónoma de Baja California, 22800 Ensenada, BC, Mexico
4School of Medicine, Universidad Autónoma de Guadalajara, 44100 Guadalajara, JAL, Mexico

Received 31 October 2015; Revised 8 January 2016; Accepted 13 January 2016

Academic Editor: Anthony DeCaprio

Copyright © 2016 Idalia Jazmin Castañeda-Yslas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. Zuñiga-Violante, E. Arellano-García, L. Camarena-Ojinaga et al., “Daño genético y exposición a plaguicidas en trabajadores agricolas del valle de san quintin, Baja California, Mexico,” Revista de Salud Ambiental, vol. 12, no. 2, pp. 93–101, 2012. View at Google Scholar
  2. A. S. Gaikwad, P. Karunamoorthy, S. J. Kondhalkar, M. Ambikapathy, and R. Beerappa, “Assessment of hematological, biochemical effects and genotoxicity among pesticide sprayers in grape garden,” Journal of Occupational Medicine and Toxicology, vol. 10, p. 11, 2015. View at Publisher · View at Google Scholar
  3. J. A. Patil, A. J. Patil, A. V. Sontakke, and S. P. Govindwar, “Occupational pesticides exposure of sprayers of grape gardens in Western Maharashtra (India): effects on liver and kidney function,” Journal of Basic and Clinical Physiology and Pharmacology, vol. 20, no. 4, pp. 335–355, 2009. View at Google Scholar · View at Scopus
  4. C. Bolognesi, A. Creus, P. Ostrosky-Wegman, and R. Marcos, “Micronuclei and pesticide exposure,” Mutagenesis, vol. 26, no. 1, pp. 19–26, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. B. García, “Reestructuración económica y feminización del mercado de trabajo en México,” Papeles de Población, vol. 27, pp. 45–61, 2001. View at Google Scholar
  6. L. Camarena Ojinaga, C. von Glascoe, C. Martínez Valdés, and E. Arellano García, “Occupational risks and health: perceptions of indigenous female agricultural workers in northwestern Mexico,” Salud Colectiva, vol. 9, no. 2, pp. 247–256, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. J. Moreno-Mena, “Los valles agricolas de Baja California: espacios de agricultura para la exportacion,” in Migración Poder y Procesos Rurales, pp. 66–77, Plaza y Valdés Editores, San Rafael, Mexico, 2008. View at Google Scholar
  8. K. Huen, K. Harley, J. Brooks et al., “Developmental changes in PON1 enzyme activity in young children and effects of PON1 polymorphisms,” Environmental Health Perspectives, vol. 117, no. 10, pp. 1632–1638, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. B. Eskenazi, K. Kogut, K. Huen et al., “Organophosphate pesticide exposure, PON1, and neurodevelopment in school-age children from the CHAMACOS study,” Environmental Research, vol. 134, pp. 149–157, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. B. Eskenazi, J. Chevrier, S. A. Rauch et al., “In utero and childhood polybrominated diphenyl ether (PBDE) exposures and neurodevelopment in the CHAMACOS study,” Environmental Health Perspectives, vol. 121, no. 2, pp. 257–262, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. J. Chevrier, B. Eskenazi, N. Holland, A. Bradman, and D. B. Barr, “Effects of exposure to polychlorinated biphenyls and organochlorine pesticides on thyroid function during pregnancy,” American Journal of Epidemiology, vol. 168, no. 3, pp. 298–310, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. N. Holland, A. Fucic, D. F. Merlo, R. Sram, and M. Kirsch-Volders, “Micronuclei in neonates and children: effects of environmental, genetic, demographic and disease variables,” Mutagenesis, vol. 26, no. 1, pp. 51–56, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. J. T. Efird, E. A. Holly, S. Preston-Martin et al., “Farm-related exposures and childhood brain tumours in seven countries: results from the search international brain tumour study,” Paediatric and Perinatal Epidemiology, vol. 17, no. 2, pp. 201–211, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Fenech, N. Holland, W. P. Chang, E. Zeiger, and S. Bonassi, “The HUman MicroNucleus Project—an international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans,” Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 428, no. 1-2, pp. 271–283, 1999. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Bonassi, E. Coskun, M. Ceppi et al., “The HUman MicroNucleus project on eXfoLiated buccal cells (HUMN XL): the role of life-style, host factors, occupational exposures, health status, and assay protocol,” Mutation Research/Reviews in Mutation Research, vol. 728, no. 3, pp. 88–97, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. O. Torres-Bugarin, M. G. Zavala-Cerna, A. Flores-Garcia, and M. L. Ramos-Ibarra, “Procedimientos básicos de la prueba de micronúcleos y anormalidades nucleares en células exfoliadas de mucosa oral,” El Residente, vol. 1, pp. 4–11, 2013. View at Google Scholar
  17. C. Bolognesi, S. Knasmueller, A. Nersesyan, P. Thomas, and M. Fenech, “The HUMNxl scoring criteria for different cell types and nuclear anomalies in the buccal micronucleus cytome assay—an update and expanded photogallery,” Mutation Research, vol. 753, no. 2, pp. 100–113, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. P. E. Tolbert, C. M. Shy, and J. W. Allen, “Micronuclei and other nuclear anomalies in buccal smears: methods development,” Mutation Research/Environmental Mutagenesis and Related Subjects, vol. 271, no. 1, pp. 69–77, 1992. View at Publisher · View at Google Scholar · View at Scopus
  19. P. E. Tolbert, C. M. Shy, and J. W. Allen, “Micronuclei and other nuclear anomalies in buccal smears: a field test in snuff users,” American Journal of Epidemiology, vol. 134, no. 8, pp. 840–850, 1991. View at Google Scholar · View at Scopus
  20. P. Thomas, N. Holland, C. Bolognesi et al., “Buccal micronucleus cytome assay,” Nature Protocols, vol. 4, no. 6, pp. 825–837, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. O. Torres-Bugarín, M. G. Zavala-Cerna, A. Nava, A. Flores-García, and M. L. Ramos-Ibarra, “Potential uses, limitations, and basic procedures of micronuclei and nuclear abnormalities in buccal cells,” Disease Markers, vol. 2014, Article ID 956835, 13 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. O. Torres-Bugarín, R. Covarrubias-Bugarín, A. L. Zamora-Perez, B. M. G. Torres-Mendoza, M. García-Ulloa, and F. G. Martínez-Sandoval, “Anabolic androgenic steroids induce micronuclei in bucca mucosa cells of bodybuilders,” British Journal of Sports Medicine, vol. 41, no. 9, pp. 592–596, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. O. Torres-Bugarín, A. Ventura-Aguilar, A. Zamora-Perez et al., “Evaluation of cisplatin + 5-FU, carboplatin + 5-FU, and ifosfamide + epirubicine regimens using the micronuclei test and nuclear abnormalities in the buccal mucosa,” Mutation Research—Genetic Toxicology and Environmental Mutagenesis, vol. 539, no. 1-2, pp. 177–186, 2003. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Gomez-Arroyo, Y. Diaz-Sanchez, M. A. Meneses-Perez et al., “Cytogenetic biomonitoring in a Mexican floriculture worker group exposed to pesticides,” Mutation Research, vol. 466, no. 1, pp. 117–124, 2000. View at Google Scholar
  25. M. C. O. Arellano, C. Von-Glascoe, B. Ruiz, E. Zuñiga, and T. Monraño, “Daño genotóxico en mujeres y hombres expuestos en cuatro localidades de Baja California,” in Instituto Nacional de Ecología. Secretaría de Medio Ambiente y Recursos Naturales (SEMARNAT), pp. 95–113, Género, Ambiente y Contaminación por Sustancias Químicas, 2012. View at Google Scholar
  26. T. Montaño-Soto, E. Arellano-García, L. Camarena-Ojinaga et al., “Genotoxic biomonitoring and exposure to pesticides in women laborers at maneadero valley in Baja California, Mexico,” International Journal of Applied and Natural Sciences, vol. 3, no. 2, pp. 89–96, 2014. View at Google Scholar
  27. C. Martinez-Valenzuela and S. Gomez-Arroyo, “Riesgo genotóxico por exposición a plaguicidas en trabajadores agrícolas,” La Revista Internacional de Contaminación Ambiental, vol. 23, pp. 185–200, 2007. View at Google Scholar
  28. R. Castro, V. Ramírez, and P. Cuenca, “Micronúcleos y otras anormalidades nucleares en el epitelio oral de mujeres expuestas ocupacionalmente a plaguicidas,” Revista de Biología Tropical, vol. 1, no. 2, pp. 611–621, 2014. View at Publisher · View at Google Scholar
  29. S.-J. Lee, L. Mehler, J. Beckman et al., “Acute pesticide illnesses associated with off-target pesticide drift from agricultural applications: 11 states, 1998–2006,” Environmental Health Perspectives, vol. 119, no. 8, pp. 1162–1169, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. M. Kirsch-Volders and M. Fenech, “Inclusion of micronuclei in non-divided mononuclear lymphocytes and necrosis/apoptosis may provide a more comprehensive cytokinesis block micronucleus assay for biomonitoring purposes,” Mutagenesis, vol. 16, no. 1, pp. 51–58, 2001. View at Publisher · View at Google Scholar · View at Scopus
  31. L. S. Benitez, M. L. Macchi, V. Fernández et al., Daño Celular en una Población Infantil Potencialmente Expuesta a Pesticidas, vol. 131, BASE Investigaciones Sociales, 2010.
  32. S. Gómez-Arroyo, C. Martínez-Valenzuela, S. Calvo-González et al., “Assessing the genotoxic risk for Mexican children who are in residential proximity to agricultural areas with intense aerial pesticide applications,” Revista Internacional de Contaminacion Ambiental, vol. 29, no. 3, pp. 217–225, 2013. View at Google Scholar · View at Scopus
  33. N. Bernardi, N. Gentile, F. Mañas, Á. Méndez, N. Gorla, and D. Aiassa, “Assessment of the level of damage to the genetic material of children exposed to pesticides in the province of Cordoba,” Archivos Latino-Americanos de Pediatría, vol. 113, no. 2, pp. 126–131, 2015. View at Publisher · View at Google Scholar
  34. M. Neri, A. Fucic, L. E. Knudsen, C. Lando, F. Merlo, and S. Bonassi, “Micronuclei frequency in children exposed to environmental mutagens: a review,” Mutation Research—Reviews in Mutation Research, vol. 544, no. 2-3, pp. 243–254, 2003. View at Publisher · View at Google Scholar · View at Scopus
  35. Health Effects Division, Office of Pesticide Programs, and US Environmental Protection Agency, “Chemicals Evaluated for Carcinogenic Potential, Science Information Management Branch,” 2006, http://www.fluoridealert.org/wp-content/pesticides/pesticides.cancer.potential.2006.pdf.
  36. WHO, World Health Organization Classification of Pesticides by Hazard, World Health Organization, Geneva, Switzerland, 2010.