Possible Protective Effect of Diacerein on Doxorubicin-Induced Nephrotoxicity in Rats

Figure 3

Photomicrographs of renal cortex immune stained for NFκB of (a), (b), and (c), control, DLD, and DHD groups, respectively, showing negative immunoreactivity. (d) DOX treated group showing extensive expression in the renal glomeruli and renal tubules. (e) DOX/DLD group showing moderate expression within the glomeruli and the renal tubules. (f) DOX/DHD group showed marked improvement with no expression in glomeruli and renal tubules. The expression is mainly cytoplasmic but with some immunopositive nuclei. Immunohistochemistry counter stained with H&E ×400. Bar = 20 μ.

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