The Hypoactivity Associated with the Repeated Exposure to Atrazine Is Related to Decreases in the Specific Binding to D1-DA Receptors in the Striatum of Rats

Figure 4

Specific binding of the antagonists [³H]-SCH23390 ((a) and (b)) and [³H]-Spiperone ((c) and (d)) to D1- and D2-DA receptors, respectively, in the striatum of rats repeatedly exposed to 100 mg ATR/kg, measured 2 days ((a) and (c)) or 2 months ((b) and (d)) after the last ATR injection. Absolute values (nmol/mg protein ± SE) for vehicle groups: (a) , (b) , (c) , and (d) ; -6. from vehicle, .

(a)

(b)

(c)

(d)