Cytotoxic and Genotoxic Effects of Acephate on Human Sperm

Table 1

Parameters	Time of exposure (h)	Treatment (µg/mL)
		0	50	100	200
Motility (%)	1	86.5 ± 2.4	82.9 ± 1.5	75.7 ± 2.7	62.0 ± 0.9
	2	79.3 ± 2.1	76.3 ± 1.9	74.1 ± 3.1	58.9 ± 2.8
	3	72.3 ± 1.9	67.3 ± 2.5	60.2 ± 2.6	37.2 ± 4.8
Viability (%)	1	88.4 ± 1.6	84.4 ± 1.2	80.4 ± 1.3	74.4 ± 1.8
	2	78.8 ± 1.0	76.5 ± 1.2	74.9 ± 1.3	62.9 ± 1.6
	3	70.8 ± 0.5	68.4 ± 1.6	66.8 ± 1.1	47.8 ± 1.4
Sperm swelling (%)	1	81.2 ± 5.3	78.9 ± 3.9	72.7 ± 2.6	65.4 ± 3.7
	2	76.6 ± 3.8	73.8 ± 2,9	68.8 ± 2.7	56.6 ± 2.9
	3	69.7 ± 2.9	69.2 ± 3.2	60.2 ± 3.1	45.2 ± 2.9
Capacitated spermatozoa (%)	1	38.5 ± 1.6	38.5 ± 1.4	36.1 ± 2.6	25.7 ± 2.7
	2	35.7 ± 2.1	33.0 ± 3.8	34.5 ± 2.6	22.5 ± 2.6
	3	33.3 ± 1.9	32.3 ± 2.6	27.3 ± 3.1	20.7 ± 2.9
DNA damage (%)	1	28.7 ± 3.1	28.3 ± 3.4	28.1 ± 2.6	30.7 ± 3.5
	2	27.3 ± 3.2	28.0 ± 2.8	28.3 ± 2.6	30.4 ± 2.7
	3	30.1 ± 3.9	33.1 ± 2.8	34.1 ± 1.9	40.0 ± 3.4

Values represent mean ± SEM (). . .