Potential Developmental and Reproductive Impacts of Triclocarban: A Scoping Review
Table 2
Human studies evaluating the developmental effects of triclocarban.
Author
Number of subjects
Age of subjects at time of exposure
Concentration detected
Exposure measurement
Summary
Geer et al., 2017
185
Adult; prenatal
0.13 µg/L (cbp); 3.44 µg/g creatinine (urine)
Maternal urine and cord blood
Cord blood plasma TCC was associated with decreased gestational age at birth in an immigrant population in Brooklyn, New York, in linear models adjusted for demographic confounders. The TCC metabolite 3′-Cl-TCC in third-trimester maternal urine was associated with fewer low birth weights.
Wei et al., 2017
92
Adult; prenatal
0.248 ng/mL (ms); 0.105 ng/mL (cs)
Maternal venous and umbilical cord blood
TCC levels were determined in a case-control study of mothers with abnormal births set in Beijing, China. Cases had one or more fetal anomalies and controls had no malformations. Levels of TCC in maternal sera were correlated with levels in cord blood. There was no difference in TCC in maternal sera or cord blood between cases and controls.
