Review Article
Potential Developmental and Reproductive Impacts of Triclocarban: A Scoping Review
Table 6
Description of recommended systematic review endpoints.
| | Number of studies | Endpoint | | Estrogenic activity | Androgenic activity | Offspring growth |
| | Human | 0 | 0 | 1 | | Rodent | 1 | 2 | 2 | | Fish | 6 | 5 | 3 | | Invertebrates | 2 | 0 | 1 | | In vitro | 5 | 7 | |
| | 14 | 14 | 9 |
| | Dose range | | | | | Human (detected) | NA | NA | 0.13 µg/L (cord blood plasma);
3.44 µg/g creatinine (urine) | | Rodent | 0.2–0.5% w/w | 0.25% w/w | 100 mM, 0.2–0.5% w/w TCC | | Aquatic | 0.045–14.0 µg/L | 0.55–10 µg/L | 0.1–10000 µg/L | | In vitro | 1 × 10−9–1 × 10−3 M | 1 × 10−9–2 × 10-3 M | 3 × 10−6–3 × 10−2 M |
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vitro/in vivo assessments counted separately, even if included in the same publication. activity.
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