Journal of Toxicology / 2019 / Article / Tab 6

Research Article

A Toxicological Evaluation of Mango Leaf Extract (Mangifera indica) Containing 60% Mangiferin

Table 6

Summary of relevant clinical chemistry findings in the 90-day study.

GroupTBILGLUCK+
mg/kg bw/day
n=10[μmol/L][mmol/L][mmol/L]

Males
ControlMean1.855.684.61
SD0.400.340.25
500Mean1.425.354.51
SD0.300.350.23
SS
1000Mean1.465.304.67
SD0.350.260.17
SS
2000Mean1.275.294.62
SD0.360.470.23
SS
test for significanceDNDNNS
historical control range0.71-2.794.58-8.243.84-5.04

Females
ControlMean2.095.334.01
SD0.400.720.16
500Mean1.695.074.03
SD0.470.590.16
SS
1000Mean1.475.054.02
SD0.320.400.18
SS
2000Mean1.464.893.85
SD0.330.560.11
SS
test for significanceDNNSDN
historical control range1.23-3.304.44-7.553.42-4.35

DN: Duncan's multiple range test; GLUC: glucose; K+: potassium; n: numbers of animals/group; NS: not significant; SD: standard deviation; SS: statistical significance; TBIL: total bilirubin.
= p < 0.05
= p < 0.01.

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