A Toxicological Evaluation of Mango Leaf Extract (Mangifera indica) Containing 60% Mangiferin
Table 6
Summary of relevant clinical chemistry findings in the 90-day study.
Group
TBIL
GLUC
K+
mg/kg bw/day
n=10
[μmol/L]
[mmol/L]
[mmol/L]
Males
Control
Mean
1.85
5.68
4.61
SD
0.40
0.34
0.25
500
Mean
1.42
5.35
4.51
SD
0.30
0.35
0.23
SS
1000
Mean
1.46
5.30
4.67
SD
0.35
0.26
0.17
SS
2000
Mean
1.27
5.29
4.62
SD
0.36
0.47
0.23
SS
test for significance
DN
DN
NS
historical control range
0.71-2.79
4.58-8.24
3.84-5.04
Females
Control
Mean
2.09
5.33
4.01
SD
0.40
0.72
0.16
500
Mean
1.69
5.07
4.03
SD
0.47
0.59
0.16
SS
1000
Mean
1.47
5.05
4.02
SD
0.32
0.40
0.18
SS
2000
Mean
1.46
4.89
3.85
SD
0.33
0.56
0.11
SS
test for significance
DN
NS
DN
historical control range
1.23-3.30
4.44-7.55
3.42-4.35
DN: Duncan's multiple range test; GLUC: glucose; K+: potassium; n: numbers of animals/group; NS: not significant; SD: standard deviation; SS: statistical significance; TBIL: total bilirubin. = p < 0.05 = p < 0.01.