Journal of Toxicology / 2019 / Article / Tab 1

Research Article

Histological, Biochemical, and Hematological Effects of Goniothalamin on Selective Internal Organs of Male Sprague-Dawley Rats

Table 1

Haematological evaluation for acute toxicity.

Control100mg/kg200mg/kg300mg/kg400mg/kg500mg/kg

Hemoglobin (g/dL)16.52 ± 1.2215.46 ± 1.1215.62 ± 1.3115.12 ± 2.2116.13 ± 1.4615.11 ± 2.08
White blood cells (109/L)6.33 ± 0.326.11 ± 0.526.61 ± 0.585.99 ± 1.146.47 ± 0535.71 ± 1.21
Neutrophils (109/L)18.22 ± 0.2318.41 ± 0.3117.17 ± 2.3517.22 ± 3.1517.30 ± 0.5018.33 ± 1.21
Lymphocyte (109/L)78.21 ± 2.2680.16 ± 5.3176.86 ± 2.1780.66 ± 3.1179.23 ± 1.1176.57 ± 1.55
Monocytes (109/L)0.89 ± 0.111.00 ± 0.100.87 ± 0.120.87 ± 0.210.85 ± 0.120.88 ± 0.10
Eosinophils (109/L)3.23 ± 3.683.13 ± 2.793.41 ± 3.213.22 ± 2.313.11 ± 2.453.51 ± 2.55
Basophils (109/L)0.01 ± 0.210.01 ± 0.110.01 ± 0.020.01 ± 0.070.01 ± 0.100.01 ± 0.06

The results are expressed as the mean ±Standard error, (n=7). No significant difference could be detected between the different groups vs. the control group; Control, normal control group; 100 mg/kg, 100 mg/kg GTN- intraperitoneal treated group; 200 mg/kg, 200 mg/kg GTN- intraperitoneal treated group; 300 mg/kg, 300 mg/kg GTN- intraperitoneal treated group; 400 mg/kg, 400 mg/kg GTN- intraperitoneal treated group; 500 mg/kg, 500 mg/kg GTN- intraperitoneal treated group.