Journal of Toxicology / 2019 / Article / Tab 7

Research Article

Histological, Biochemical, and Hematological Effects of Goniothalamin on Selective Internal Organs of Male Sprague-Dawley Rats

Table 7

Haematological evaluation of GTN-treated sub-acute toxicity.

ControlGTN-treated

Creatinine (µmol/L)25.22 ± 1.1326.24 ± 1.14
Urea (mmol/L)5.95 ± 0.335.85 ± 0.15
Albumin (g/L)35.9 ± 3.233.2 ± 4.3
Globulin (g/L)23.2 ± 2.821.3 ± 3.9
Total bilirubin (µmol/L)2.0 ± 0.82.1 ± 0.9
Alkaline phosphatase (U/L)13.9 ± 1.114.2 ± 0.5
Alanine aminotransferase (U/L)118 ± 31115 ± 12
Aspartate aminotransferase (U/L)99.5 ± 5.6100 ± 7.1

The results are expressed as the mean ± Standard error, (n=7). No significant difference could be detected between the GTN-treated group vs the control group. Control, the normal control group; GTN-treated, 42 mg/kg intraperitoneal GTN-treated group.