Research Article

Pituranthos chloranthus Oil as an Antioxidant-Based Adjuvant Therapy against Cisplatin-Induced Nephrotoxicity

Table 1

Effect of PC on serum parameters ALT, AST, and creatinine levels, in cisplatin-treated mice.

ALT (U/L)AST (U/L)Creatinine (µmol/L)

Vehicle142,75 ± 20,049,33 ± 8,126 ± 10,5
CP348 ± 22,5###112 ± 6,9##42 ± 10,9##
CP + PC 5 mg/kg319 ± 46,569 ± 2,727 ± 1,4
CP + PC 10 mg/kg271,5 ± 23,259 ± 14,328 ± 2,4

Results are mean ± SD (n = 6). and mean significant difference between treated animals and the cisplatin-treated group (CP). and mean significant difference between vehicle and the cisplatin-treated group (CP).