Research Article

Subacute Hepatotoxicity of Extracts of Senna occidentalis Seeds in Swiss Albino Mice

Table 1

Absolute and relative organ weight (g) during a 28-day subacute toxicity study on S. occidentalis seed extract compared to control group.

GroupsAbsolute liver weight (g)% increaseRelative liver weight (g)% increase

Control2.1 ± 0.04406.4 ± 0.110
400 mg/kg2.14 ± 0.089 (0.883)46.94 ± 0.27 (0.204)54
1000 mg/kg2.36 ± 0.064 (0.036)267.69 ± 0.25 (0.003)129

Data are presented as mean ± SEM. Statistical significance is shown in parenthesis and asterisks show significant difference from the control: ; .