Clerodendrum volubile Ethanol Leaf Extract: A Potential Antidote to Doxorubicin-Induced Cardiotoxicity in Rats

Table 1

Group treatment of rats.

Groups	Treatments
Group I	10 ml/kg of distilled water p.o. for 14 days + 2.5 mg/kg of doxorubicin hydrochloride in 0.9% normal saline given i.p. on alternate days for 14 days
Group II	200 mg/kg/day of Clerodendrum volubile ethanol leaf extract in 5% DMSO-distilled water p.o. for 14 days + 1 ml/kg of 0.9% normal saline given i.p. on alternate days for 14 days
Group III	50 mg/kg/day of Clerodendrum volubile ethanol leaf extract in 5% DMSO-distilled water p.o. for 14 days + 2.5 mg/kg of doxorubicin hydrochloride in 0.9% normal saline given i.p. on alternate days for 14 days
Group IV	100 mg/kg/day of Clerodendrum volubile ethanol leaf extract in 5% DMSO-distilled water p.o. for 14 days + 2.5 mg/kg of doxorubicin hydrochloride in 0.9% normal saline given i.p. on alternate days for 14 days
Group V	200 mg/kg/day of Clerodendrum volubile ethanol leaf extract in 5% DMSO-distilled water p.o. for 14 days + 2.5 mg/kg of doxorubicin hydrochloride in 0.9% normal saline given i.p. on alternate days for 14 days
Group VI	400 mg/kg/day of Clerodendrum volubile ethanol leaf extract in 5% DMSO-distilled water p.o. for 14 days + 2.5 mg/kg of doxorubicin hydrochloride in 0.9% normal saline given i.p. on alternate days for 14 days
Group VII	20 mg/kg/day of vitamin C in distilled water p.o. for 14 days + 2.5 mg/kg of doxorubicin hydrochloride in 0.9% normal saline given i.p. on alternate days for 14 days
Group VIII	10 ml/kg/day of distilled water p.o. for 14 days + 1 ml/kg of 0.9% normal saline given i.p