Reproductive Toxicity of Theobroma cacao: Increase in Survival Index, Nongenotoxic, and Proimplantation Potential

Table 2

Influence of UNCP on the level of DNA damage (tail DNA%) in tissues and organs of male C57Bl/6 mice.

Tissue
Organ	The epithelium of the rectum (tail DNA, %)	Liver (tail DNA, %)	Bone marrow (tail DNA, %)	Kidney (tail DNA, %)
UNCP:9000 mg/kg (high dose)
M ± SEM	2.32 ± 0.32	2.19 ± 0.26	2.49 ± 0.25	2.79 ± 0.35
UNCP:900 mg/kg (therapeutic dose)
M ± SEM	2.64 ± 0.17	1.64 ± 0.26	2.58 ± 0.32	1.63 ± 0.30
The negative control (solvent, 1% starch)
M ± SEM	2.17 ± 0.18	1.95 ± 0.22	1.86 ± 0.26	2.08 ± 0.27
Positive control (methyl methanesulfonate 40 mg/kg)
M ± SEM	16.58 ± 0.63	14.63 ± 0.73	16.02 ± 1.23	12.49 ± 1.25