Reproductive Toxicity of Theobroma cacao: Increase in Survival Index, Nongenotoxic, and Proimplantation Potential

Table 8

Changes in pub weights from female rats crossed with males that received UNCP for 48 days prior to mating.

Litter size		PND
Group	Sex	4th day	7th day	14th day	21st day	28th day
Cocoa HD	♀	8.63 ± 0.73	12.73 ± 0.92	24.83 ± 1.07	33.75 ± 2.55	60.35 ± 4.45
	♂	9.02 ± 0.75	13.29 ± 0.99	25.46 ± 1.13	35.10 ± 2.73	64.03 ± 5.27
Cocoa TD	♀	7.78 ± 0.81	10.84 ± 0.93	21.64 ± 0.99	30.68 ± 0.90	51.53 ± 1.95
	♂	8.42 ± 0.51	11.88 ± 0.77	22.95 ± 0.56	30.81 ± 0.87	50.34 ± 3.04
Vehicle control	♀	7.94 ± 0.68	12.38 ± 1.11	24.64 ± 2.68	34.29 ± 5.32	60.35 ± 9.10
	♂	8.60 ± 0.70	12.80 ± 1.10	25.93 ± 2.97	35.87 ± 5.37	62.95 ± 9.55