Clinical Study

Adherence to Artesunate-Amodiaquine Therapy for Uncomplicated Malaria in Rural Ghana: A Randomised Trial of Supervised versus Unsupervised Drug Administration

Table 1

Age, sex, and educational characteristics of study participants.

Supervised ( )Unsupervised ( )

Number of respondents211190
Mean age, years (95 CI)38.1 (37.7–40.4),39.5 (37.1–41.9)
Sex
Males34.6 (73)36.8 (70)
Females65.4 (138)63.2 (120)
Educational background
None44.5 (94)53.7 (102)
Primary20.9 (44)16.8 (32)
Middle school, JSS29.4 (62)27.4 (52)
Technical/commercial/SSS/post Sec 5.2 (11) 2.1 (4)
Physical Examination
Mean weight, Kg (95 CI)49.6 (48.5–50.7)49.7 (48.7–50.7)
Mean temperature (95 CI)37.9 (37.8–38.0)38.0 (37.9–38.0)
Biochemical
Proportion with sexual parasite ( ) 2.4 (5/211) 3.2 (6/190)
Mean hemoglobin, g/dL (95 CI)12.4 (12.1–12.6)12.4 (11.4–13.3)
Geometric mean ALT, U/L (95 CI) 9.0 (7.9, 10.2) 8.7 (7.6, 10.1)
Geometric mean AST, U/L (95 CI)35.0 (32.9, 37.1)35.9 (33.6, 38.3)
Geometric mean TBil, μmol/L (95 CI)12.2 (11.1, 13.5)11.6 (10.3, 13.1)
Geometric mean Ure, mmol/L (95 CI) 3.1 (2.9, 3.3) 2.8 (2.6, 3.0)
Geometric mean Cre, μmol/L ( 95 CI)68.8 (66.2, 71.5)67.7 (65.4, 70.1)

ALT : Alanine transaminase, AST : Aspartate transaminase, TBil : Total transaminase, Ure : Urea, Cre   Creatinine, 95 CI : 95 Confidence Interval.