Investigation of Association between Susceptibility to Leprosy and SNPs inside and near the BCHE Gene of Butyrylcholinesterase

Table 3

Haplotype^a frequencies compared between contact control (C) and patient (P) samples.

		SNPs^b				Samples (%)		𝜒^2; 𝑃 (Bonferroni’s correction)
rs2863381	rs4440084	rs1126680	rs1799807 (𝐷70G)	rs1803274 (𝐴539𝑇)	rs4387996	C	P
T	G	G	A	G	G	24.9	25.1	n.s.
T	G	G	A	G	A	12.0	13.8	n.s.
T	C	G	A	G	G	11.6	18.5	5.28; 0.0216 (0.151)
T	C	G	A	G	A	9.5	3.4	8.62; 0.0033 (0.023)
C	C	G	A	G	G	8.9	3.8	6.69; 0.0097 (0.068)
C	C	G	A	G	A	8.1	6.5	n.s.
C	G	G	A	G	G	7.1	6.5	n.s.

^aSelected on the basis of frequency higher than 5% at least in one of the samples. ^bMost frequent nucleotides in Caucasians from the HapMap: rs2863381 (𝑇), rs4440084 (𝐺), rs1126680 (𝐺), rs1799807 (𝐴), rs1803274 (𝐺), and rs4387996 (𝐺).