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Journal of Tropical Medicine
Volume 2012, Article ID 614820, 7 pages
http://dx.doi.org/10.1155/2012/614820
Review Article

Mechanism of Trypanosoma cruzi Placenta Invasion and Infection: The Use of Human Chorionic Villi Explants

1Department of Histology and Embryology, Faculty of Medicine, Universidad Nacional Córdoba, 5000 Cordoba, Argentina
2IICSHUM and Cathedra of Histology, Embryology and Genetic, Health Department, Universidad Nacional La Rioja, 5300 La Rioja, Argentina
3Program of Anatomy and Developmental Biology, Institute for Biomedical Sciences, Faculty of Medicine, University of Chile, 8380453 Santiago, Chile

Received 28 November 2011; Revised 6 February 2012; Accepted 14 February 2012

Academic Editor: Demba Sarr

Copyright © 2012 Ricardo E. Fretes and Ulrike Kemmerling. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [12 citations]

The following is the list of published articles that have cited the current article.

  • C. Castillo, R. Lopez-Munoz, J. Duaso, N. Galanti, F. Jana, J. Ferreira, G. Cabrera, J. D. Maya, and U. Kemmerling, “Role of matrix metalloproteinases 2 and 9 in ex vivo Trypanosoma cruzi infection of human placental chorionic villi,” Placenta, vol. 33, no. 12, pp. 991–997, 2012. View at Publisher · View at Google Scholar
  • Paulo Camara Marques Pereira, and Elaine Cristina Navarro, “Challenges and perspectives of Chagas disease: a review,” Journal Of Venomous Animals And Toxins Including Tropical Diseases, vol. 19, 2013. View at Publisher · View at Google Scholar
  • Christian Castillo, Arturo Villarroel, Juan Duaso, Norbel Galanti, Gonzalo Cabrera, Juan Diego Maya, and Ulrike Kemmerling, “Phospholipase C gamma and ERK1/2 Mitogen Activated Kinase Pathways are differentially modulated by Trypanosoma cruzi during tissue invasion in human placenta,” Experimental Parasitology, vol. 133, no. 1, pp. 12–17, 2013. View at Publisher · View at Google Scholar
  • Ana Liempi, Christian Castillo, Mauricio Cerda, Daniel Droguett, Juan Duaso, Katherine Barahona, Ariane Hernández, Cintia Díaz-Luján, Ricardo Fretes, Steffen Härtel, and Ulrike Kemmerling, “Trypanosoma cruzi infectivity assessment in “in vitro” culture systems by automated cell counting,” Acta Tropica, 2014. View at Publisher · View at Google Scholar
  • Gemma Rojo, Christian Castillo, Juan Duaso, Ana Liempi, Daniel Droguett, Norbel Galanti, Juan Diego Maya, Rodrigo López-Muñoz, and Ulrike Kemmerling, “Toxic and therapeutic effects of Nifurtimox and Benznidazol on Trypanosoma cruzi ex vivo infection of human placental chorionic villi explants,” Acta Tropica, 2014. View at Publisher · View at Google Scholar
  • C Díaz-Luján, Mf Triquell, C Castillo, D Hardisson, U Kemmerling, and Re Fretes, “Role of placental barrier integrity in infection by Trypanosoma cruzi,” Acta Tropica, 2016. View at Publisher · View at Google Scholar
  • Miguel Hernán Vicco, Luz Rodeles, Gabriela Soledad Capovilla, Melina Perrig, Ana Gabriela Herrera Choque, Iván Marcipar, Oscar Bottasso, Celeste Rodriguez, and Washington Cuña, “IgG Autoantibodies Induced by T. cruzi During Pregnancy: Correlation with Gravidity Complications and Early Outcome Assessment of the Newborns,” Maternal and Child Health Journal, 2016. View at Publisher · View at Google Scholar
  • Christian Castillo, Lorena Muñoz, Ileana Carrillo, Ana Liempi, Lisvaneth Medina, Norbel Galanti, Juan Diego Maya, and Ulrike Kemmerling, “Toll- like receptor-2 mediates local innate immune response against Trypanosoma cruzi in ex vivo infected human placental chorionic villi explants,” Placenta, 2017. View at Publisher · View at Google Scholar
  • Lisvaneth Medina, Christian Castillo, Ana Liempi, Mathias Herbach, Gonzalo Cabrera, Lucía Valenzuela, Norbel Galanti, María de los Angeles Curto, Alejandro G. Schijman, and Ulrike Kemmerling, “Differential infectivity of two Trypanosoma cruzi strains in placental cells and tissue,” Acta Tropica, 2018. View at Publisher · View at Google Scholar
  • Natalia Anahí Juiz, Irma Torrejón, Marianela Burgos, Ana María Fernanda Torres, Tomás Duffy, Nelly Melina Cayo, Anahí Tabasco, Miriam Salvo, Silvia Andrea Longhi, and Alejandro Gabriel Schijman, “Alterations in Placental Gene Expression of Pregnant Women With Chronic Chagas Disease,” The American Journal of Pathology, 2018. View at Publisher · View at Google Scholar
  • María Fernanda Triquell, Cintia Díaz-Luján, María Cristina Romanini, Juan Carlos Ramirez, Patricia Paglini-Oliva, Alejandro Gabriel Schijman, and Ricardo Emilio Fretes, “ Nitric oxide synthase and oxidative-nitrosative stress play a key role in placental infection by Trypanosoma cruzi ,” American Journal of Reproductive Immunology, pp. e12852, 2018. View at Publisher · View at Google Scholar
  • Jatziri Torres-Vargas, Karla Y. Acosta-Viana, Eugenia Guzmán-Marín, Zaida E. Yadon, José Leonardo Guillermo-Cordero, Antonio Ortega-Pacheco, Matilde Jiménez-Coello, Eduardo Gutiérrez-Blanco, and Nisha J. Garg, “Quantitative and histological assessment of maternal-fetal transmission of Trypanosoma cruzi in guinea pigs: An experimental model of congenital Chagas disease,” PLoS Neglected Tropical Diseases, vol. 12, no. 1, 2018. View at Publisher · View at Google Scholar