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Journal of Tropical Medicine
Volume 2012, Article ID 787240, 5 pages
http://dx.doi.org/10.1155/2012/787240
Clinical Study

The Comparition of the Efficacy of Two Different Probiotics in Rotavirus Gastroenteritis in Children

1Department of Pediatrics, Medical Faculty, Bezmialem Vakif University, Adnan Menderes Bulvarı, P.K.: 34093 Fatih, Istanbul, Turkey
2Department of Neonatal Intensive Care Unit, Medical Faculty, Bezmialem Vakif University, Istanbul, Turkey

Received 6 March 2012; Revised 20 April 2012; Accepted 3 May 2012

Academic Editor: Marcel Tanner

Copyright © 2012 Özlem Erdoğan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives. The aim of the study is to compare the clinical effectiveness of the probiotics—Saccharomyces boulardii and Bifidobacterium lactis—in children who had been diagnosed with rotavirus gastroenteritis. Materials and methods. Seventy five patients aged between 5 months–5 years diagnosed as rotavirus gastroenteritis were included in the study. The patients diagnosed as rotavirus gastroenteritis by latex agglutination test in stool were divided into 3 groups of twenty-five patients each: First group was given oral rehydration therapy and rapid refeeding with a normal diet with Saccharomyces boulardii (spp. I-745), second group was given oral rehydration therapy and rapid refeeding with a normal diet with Bifidobacterium lactis (spp. B94, culture number: 𝑁 1 1 8 5 2 9 ) and third group received only oral rehydration therapy and rapid refeeding with a normal diet. Results. The duration of diarrhea was shorter in the group given oral rehydration therapy and rapid refeeding with a normal diet with Bifidobacterium lactis and Saccharomyces boulardii than the group given only oral rehydration therapy and rapid refeeding with a normal diet. Conclusion. Bifidobacterium lactis has a complemental role in the treatment of rotavirus gatroenteritis and other probiotics may also have a beneficial effect in rotavirus gastroenteritis compared with the therapy included only oral rehydration therapy and rapid refeeding with a normal diet.