Immunological Consequences of Antihelminthic Treatment in Preschool Children Exposed to Urogenital Schistosome Infection

Figure 1

Change in anti-schistosome antibody titers (optical densities). Serum IgM (a); IgE (b) and IgG4 (c) against adult worm (SWAP), cercariae (CAP), and egg (SEA) antigens are plotted as lines connecting pre- (baseline) and post- (6 weeks) treatment levels for treated and untreated children. Participants who were egg positive at baseline are highlighted in grey thick lines. Stars represent significant difference of mean absorbencies at ^∗∗𝑃<0.01 or ^∗𝑃<0.05. The cut-off points for IgM are highlighted with dashed horizontal lines (a).

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