Reversible Audiometric Threshold Changes in Children with Uncomplicated Malaria

Table 1

Median hearing threshold levels on day 0 (before treatment).

Frequency	Group	Left ear			Right ear
		Median	IQR	𝑃-value	Median	IQR	𝑃-value
125	ASAQ	30	27.5–35	0.001	30	25–40	0.001
	AML	40	30–40		40	30–40
	AQ	35	35–37.5		40	30–42.5
	CTRL	25	20–30		25	20–30
250	ASAQ	40	35–45	0.001	35	35–41.25	0.001
	AML	42.5	37.5–45		45	32.5–50
	AQ	45	43.75–45		40	36.25–46.25
	CTRL	25	20–30		30	20–30
500	ASAQ	40	35–40	0.001	40	35–41.25	0.001
	AML	40	37.5–50		40	32.7–47.5
	AQ	45	38.75–45		45	42.5–46.25
	CTRL	25	20–30		25	20–30
750	ASAQ	35	30–40	0.001	30	30–40	0.001
	AML	40	35–45		37.5	30–40
	AQ	40	33.75–41.25		40	36.25–45
	CTRL	25	20–30		25	20–26.25
1000	ASAQ	30	20–30	0.001	25	22.5–32.5	0.001
	AML	32.5	30–35		30	27.5–35
	AQ	35	30–35		35	26.25–36.25
	CTRL	20	15–25		20	15–25
1500	ASAQ	25	25–30	0.001	20	20–28.75	0.001
	AML	30	25–30		30	21.25–20
	AQ	25	23.75–31.25		27.5	20–30
	CTRL	15	13.75–20		15	15–21.25
2000	ASAQ	20	15–20	0.001	20	15–20	0.001
	AML	20	20–30		20	17.5–27.5
	AQ	20	20–25		20	12.5–26.25
	CTRL	15	10–20		15	10–20
3000	ASAQ	20	10–21.25	0.001	15	13.75–20	0.001
	AML	20	15–25		20	15–27.5
	AQ	20	15–22.5		15	13.75–20
	CTRL	15	8.75–15		10	7.5–15
4000	ASAQ	15	10–21.25	0.001	15	15–20	0.001
	AML	20	15–25		20	15–25
	AQ	15	15–21.25		15	13.75–16.25
	CTRL	10	10–16.25		10	5–15
6000	ASAQ	20	13.75–25	0.09	15	10–26.5	0.13
	AML	22.5	20–30		20	10–30
	AQ	20	13.75–21.25		15	6.25–21.25
	CTRL	15	10–20		15	10–20
8000	ASAQ	10	5–16.25	0.02	15	10–15	0.02
	AML	15	10–25		15	10–20
	AQ	20	13.75–28.75		15	5–20
	CTRL	10	5–15		10	3.75–15

ASAQ = artesunate + amodiaquine; AML: artemether-lumefantrine; AQ: amodiaquine; CTRL: control group.