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Journal of Tropical Medicine
Volume 2014, Article ID 161284, 6 pages
http://dx.doi.org/10.1155/2014/161284
Research Article

Prevalence of Plasmodium falciparum Parasitaemia and Its Correlation with Haematological Parameters among HIV-Positive Individuals in Nigeria

1Department of Medical Microbiology & Parasitology, Ladoke Akintola University of Technology, PMB 4400, Osogbo, Nigeria
2Department of Biomedical Science, Ladoke Akintola University of Technology, PMB 4400, Osogbo, Nigeria
3Department of Mathematical and Physical Sciences, Osun State University, PMB 4494, Osogbo, Nigeria

Received 5 November 2013; Revised 26 January 2014; Accepted 27 January 2014; Published 4 March 2014

Academic Editor: Aditya Prasad Dash

Copyright © 2014 Olusola Ojurongbe et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Malaria and HIV are the two most important health challenges of our time. Haematologic abnormalities are features in Plasmodium falciparum infection, and anaemia is a well-known outcome. The prevalence and haematological impact of P. falciparum parasitaemia were determined among HIV-infected individuals in Nigeria. Parasite detection was carried out using microscopy and Polymerase Chain Reaction (PCR). Haemoglobin concentration was determined using an automated machine while CD4+ T-cells count was analyzed using flow cytometer. Thirty-seven (18.5%) out of the 200 HIV individuals enrolled had malaria parasites detected in their blood. All the positive cases were detected by PCR while only 20 (10%) were detected by thick blood microscopy. The mean haemoglobin concentration and packed cell volume (PCV) of HIV individuals with malaria parasitaemia were lower compared to those without malaria parasitaemia but the difference was not statistically significant. Also no significant difference was observed in malaria positivity in respect to sex and mean CD4+ cell count. The study highlights the effects of P. falciparum parasitaemia on the haematologic and immune components of HIV individuals.