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Journal of Tropical Medicine
Volume 2016 (2016), Article ID 7439605, 6 pages
Research Article

Neonatal Tetanus Immunity in Nigeria: The Effect of HIV Infection on Serum Levels and Transplacental Transfer of Antibodies

1Department of Paediatrics, Abubakar Tafawa Balewa University Teaching Hospital, Bauchi 740222, Nigeria
2Department of Paediatrics, University of Maiduguri, Maiduguri 600243, Nigeria
3Department of Microbiology, University of Maiduguri, Maiduguri 600243, Nigeria
4Department of Paediatrics, Federal Medical Centre Yola, Yola 640101, Nigeria

Received 22 November 2015; Accepted 20 December 2015

Academic Editor: Marcel Tanner

Copyright © 2016 Muhammad Faruk Bashir et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. D. Gupta and P. M. Keyl, “Effectiveness of prenatal tetanus toxoid immunization against neonatal tetanus in a rural area in India,” Pediatric Infectious Disease Journal, vol. 17, no. 4, pp. 316–321, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. K. W. Newell, L. A. Duenas, D. R. LeBlanc, and N. Garces Osorio, “The use of tetanus toxoid for the prevention of neonatal tetanus in developing countries for the prevention of tetanus neonatorum,” Bulletin of the World Health Organization, vol. 35, pp. 863–871, 1966. View at Google Scholar
  3. R. E. Black, D. H. Huber, and G. T. Curlin, “Reduction of neonatal tetanus by mass immunization of non-pregnant women: duration of protection provided by one or two doses of aluminium-adsorbed tetanus toxoid,” Bulletin of the World Health Organization, vol. 58, no. 6, pp. 927–930, 1980. View at Google Scholar
  4. G. G. Berggren, W. Berggren, and A. Verly, “Traditional midwives, tetanus immunization, and infant mortality in rural Haiti,” Tropical Doctor, vol. 13, no. 2, pp. 79–87, 1983. View at Google Scholar · View at Scopus
  5. J. Cliff, “Neonatal tetanus in Maputo, Mozambique Part II. Preventative measures,” Central African Journal of Medicine, vol. 31, no. 2, pp. 27–31, 1985. View at Google Scholar · View at Scopus
  6. J. Vandelaer, M. Birmingham, F. Gasse, M. Kurian, C. Shaw, and S. Garnier, “Tetanus in developing countries: an update on the maternal and neonatal tetanus elimination initiative,” Vaccine, vol. 21, no. 24, pp. 3442–3445, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. T. N. Dieye, P. S. Sow, T. Simonart et al., “Immunologic and virologic response after tetanus toxoid booster among HIV-1 and HIV-2-infected Senegalese individuals,” Vaccine, vol. 20, no. 5-6, pp. 905–913, 2002. View at Publisher · View at Google Scholar · View at Scopus
  8. T. C. S. Bonetti, R. C. M. Succi, L. Y. Weckx, L. Tavares-Lopes, and M. I. De Moraes-Pinto, “Tetanus and diphtheria antibodies and response to a booster dose in Brazilian HIV-1-infected women,” Vaccine, vol. 22, no. 27-28, pp. 3707–3712, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. B. J. Okoko, L. H. Wesuperuma, M. O. Ota et al., “Influence of placental malaria infection and maternal hypergammaglobulinaemia on materno-fetal transfer of measles and tetanus antibodies in a rural west African population,” Journal of Health, Population, and Nutrition, vol. 19, no. 2, pp. 59–65, 2001. View at Google Scholar · View at Scopus
  10. M. I. De Moraes-Pinto, F. Verhoeff, L. Chimsuku et al., “Placental antibody transfer: influence of maternal HIV infection and placental malaria,” Archives of Disease in Childhood: Fetal and Neonatal Edition, vol. 79, no. 3, pp. F202–F205, 1998. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Cumberland, C. E. Shulman, P. A. C. Maple et al., “Maternal HIV infection and placental malaria reduce transplacental antibody transfer and tetanus antibody levels in newborns in Kenya,” Journal of Infectious Diseases, vol. 196, no. 4, pp. 550–557, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. WHO, “Immunisation, surveillance, assessment, and monitoring,” Maternal and Neonatal Tetanus (MNT) Elimination: 1–7, 2010.
  13. W. G. Cochran, Sampling Techniques, John Wiley & Sons, New York, NY, USA, 3rd edition, 1977.
  14. N. U. Adabara, Y. T. Kandakai-Olukemi, M. N. Enenebeaku, and P. H. Daru, “Assessment of materno-foetal transfer of antitetanus immunoglobulin G in Jos University Teaching Hospital, Jos,” Shiraz E Medical Journal, vol. 11, no. 2, pp. 1–8, 2010. View at Google Scholar
  15. B. J. Stoll and I. Adams-Chapman, “The high-risk infant,” in Nelson Textbook of Pediatrics, R. M. Kliegman, R. E. Behrman, H. B. Jenson, and B. F. Stanton, Eds., p. 97, Saunders, 18th edition, 2007. View at Google Scholar
  16. G. A. Oyedeji, “Socioeconomic and cultural background of hospitalized children in Ilesha,” Nigerian Journal of Paediatrics, vol. 12, no. 4, pp. 111–117, 1985. View at Google Scholar
  17. Product Information Instruction Manual. Enzyme Immunoassay for the Detection and the Quantitative Determination of Human IGG Antibodies against Tetanus Toxoid in Serum and Plasma, Demeditec Diagnostics, Kiel, Germany, 2009.
  18. WHO, “Tetanus vaccine: WHO position paper,” The Weekly Epidemiological Record, vol. 81, pp. 198–208, 2006. View at Google Scholar
  19. WHO, “Global program on AIDS—recommendations for the selection and use of HIV antibody tests,” Weekly Epidemiological Record, vol. 20, pp. 145–149, 1992. View at Google Scholar
  20. Federal Republic of Nigeria, Global AIDS Response Country Progress Report, Nigeria, 2012,
  21. C. T. Omisakin, A. J. Esan, K. A. Fasakin et al., “Syphilis and Human Immunodeficiency virus co-infection among pregnant women in Nigeria: prevalence and trend,” International STD Research & Reviews, vol. 2, no. 2, pp. 94–100, 2014. View at Publisher · View at Google Scholar
  22. C. M. Chama, M. Bello, B. A. Ajayi, S. Zarma, and W. Gashau, “The use of highly active antiretroviral therapy for the prevention of mother-to-child transmission of the human immunodeficiency virus in Nigeria,” Journal of Obstetrics and Gynaecology, vol. 30, no. 4, pp. 362–366, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. NACP, “National HIV prevalence sentinels survey among pregnant women in Nigeria,” Tech. Rep., Department of Public Health, NACP, FMOH, 2010. View at Google Scholar
  24. N. Hood, M. C. K. Chan, S. M. Maxwell, J. B. Familusi, and C. A. Hart, “Placental transfer of tetanus toxoid antibodies in Nigerian mothers,” Annals of Tropical Paediatrics, vol. 14, no. 3, pp. 179–182, 1994. View at Google Scholar · View at Scopus
  25. F. T. Cutts, L. C. Rodriguez, S. Colombo, and S. Bennett, “Evaluation of factors influencing vaccine uptake in Mozambique,” International Journal of Epidemiology, vol. 18, no. 2, pp. 427–433, 1989. View at Publisher · View at Google Scholar · View at Scopus
  26. J. L. Michaux, J. F. Heremans, and W. H. Hitzig, “Immunoglobulin levels in cord-blood serum of negroes and Caucasians,” Tropical and Geographical Medicine, vol. 18, no. 1, pp. 10–14, 1966. View at Google Scholar · View at Scopus
  27. V. Sangpetchsong, S. Vichaikummart, A. Vichitnant, and A. Podhipak, “Transfer rate of transplacental immunity to tetanus from non-immunized and immunized mothers,” Southeast Asian Journal of Tropical Medicine and Public Health, vol. 15, no. 3, pp. 275–280, 1984. View at Google Scholar · View at Scopus
  28. S. Y. Maselle, “Maternal and foetal tetanus toxoid antibody levels following immunization in pregnancy,” Journal of Obstetrics and Gynaecology of Eastern and Central Africa, vol. 8, pp. 11–14, 1989. View at Google Scholar