Liver Fibrosis and Hepatitis B Coinfection among ART Naïve HIV-Infected Patients at a Tertiary Level Hospital in Northwestern Tanzania: A Cross-Sectional Study

Table 1

Baseline sociodemographic and clinical characteristics of 743 enrolled ART naïve patients.

Characteristic	All patients (); Number (%) or median (IQR)	HIV-monoinfected (); Number (%) or median (IQR)	HBV/HIV coinfected (); Number (%) or median (IQR)	Odds ratio; (95% CI)	value
Sex
Males	259 (34.9)	242 (34.8)	17 (34.7)	0.99 (0.54–1.82)	0.98
Age (years)	37 (IQR 30–44)	37 (30–44)	38 (30–43)	0.99 (0.97–1.02)	0.83
≥39	329 (44.28)	309 (44.52)	20 (40.82)	1.26 (1.01–1.45)	0.002
Age group ≥ 39	45 (41–51)	45 (41–51)	47.5 (41–51)	1.00 (0.95–1.06)	0.91
Age group < 39	31 (25–35)	31 (25–35)	30 (26–36)	1.01 (0.95–1.1)	0.75
Marital status
Single	189 (25.4)	175 (25.2)	14 (28.6)	1.19 (0.62–2.26)	0.61
Married	300 (40.4)	281 (40.5)	19 (38.8)	0.93 (0.51–1.69)	0.81
Divorced	132 (17.8)	121 (17.4)	11 (22.5)	0.37 (0.68–2.78)	0.38
Widowed	122 (16.4)	117 (16.9)	5 (10.2)	0.56 (0.22–1.44)	0.23
AIDS stage
1 or 2	386 (51.9)	367 (52.9)	19 (38.8)
3 or 4	357 (48.1)	327 (47.1)	30 (61.2)	1.77 (0.98–3.21)	0.006
Baseline CD4 (cells/µl)	256 (123–458)	266 (132–465)	158 (88.5–295)	1.46 (0.76–2.84)	0.02
CD4 < 200	251 (33.8)	218 (31.4)	33 (67.4)	4.50 (2.43–8.36)	<0.001
CD4 ≥ 200 group	400 (290–591)	513 (308–583)	399 (286–594)	1.00 (0.99–1.00)	1.00
CD4 < 200 group	91 (37–151)	123 (49–162)	87 (36–150)	1.00 (0.99–1.01)	0.23
Liver enzymes (IU/l)
AST	26 (19.5–37)	26 (19.6–37)	30.2 (18.8–57.3)	1.01 (1.00–1.02)	<0.001
AST > 40	254 (34.2)	230 (33.1)	24 (48.5)	1.94 (1.08–3.46)	0.03
ALT	19 (13–30)	18.3 (13–29)	25.9 (13–45)	1.01 (1.00–1.02)	0.02
ALT > 41	203 (27.32)	182 (26.22)	21 (42.86)	2.11 (1.17–3.81)	0.01
Platelets (cells/ul)	247 (189–330) × 10^3	250 (191–331) × 10^3	203 (170–275) × 10^3	1.04 (0.83–1.05)	0.05
<150 × 10^3	63 (8.5)	56 (8.1)	7 (14.3)	0.53 (0.23–1.23)	0.14