Developing Small Molecule Therapeutics for the Initial and Adjunctive Treatment of Snakebite

Figure 4

Hit to Lead: a variety of strategies to discover new SMTs and an example of processes and targets for High Throughput Screening (HTS) of candidate snake venom SMTs. sPLA₂, svMP, and SP serve as examples of potential targets. Different assay methods are used for each type of enzymatic activity so screens would be run separately even if compound libraries were the same.