Review Article

Developing Small Molecule Therapeutics for the Initial and Adjunctive Treatment of Snakebite

Table 2

Generic pathogenesis of major toxins in snake venom: secreted phospholipase A2 (sPLA2), metallo- and serine-proteases (svMP and SP), and the nonenzymatic three-finger toxins (3-FTX).

FamilysPLA2svMPSP3-FTX

NeurotoxicYes--Yes
HemotoxicYesYesYes-
MyotoxicYesYes--
CytotoxicYesYes-Yes