Interferon-γ and Interleukin-10 Responses during Clinical Malaria Episodes in Infants Aged 0–2 Years Prenatally Exposed to Plasmodium falciparum: Tanzanian Birth Cohort

Table 1

Geometric mean of IL-10 and IFN-γ response at baseline (in cord blood) and during clinical malaria episodes.

Cytokine	Mean pg/ml (95% CI) of infants born to pm+ mothers (n=50)	Mean pg/ml (95% CI) of infants born to pm- mothers (n=165)	P value
BL IL-10	5.4 (4.5-6.4)	5.7 (4.7-6.7)	0.74
BL IFN-γ	407.1 (366.5-447.6)	390.2 (355.5-424.9)	0.54
DCME 1L-10	22.4 (19.4-28.4)	15.1 (12.4-17.6)	0.001
DCME IFN-γ	557.9 (511.6-604.1)	634.4 (618.2-668.5)	0.002

BL: baseline levels, DCME: during clinical malaria episodes, CI: confidence interval. The statistical P value was obtained using independent-samples t-test.