Antimalarial Activity of Piperine

Table 2

Antimalarial activities expressed as IC₅₀ values of piperine, chloroquine, mefloquine, and artesunate in 3D7 and K1 P. falciparum clones. Data are presented as median (range) value of three independent experiments, triplicate each.

Compounds	Median IC50 (range)
	3D7	K1
Piperine (uM)	111.5 (103.3-117.0)	59.0 (55.0-70.0)
Chloroquine (nM)	3.9 (3.5-4.0)	115.0 (114.9-135.4)
Mefloquine (nM)	14.6 (13.8-17.3)	4.22 (3.93-4.83)
Artesunate (nM)	2.48 (1.84-3.01)	1.06 (1.06-1.17)