Research Article
The Incidence of Non-Tuberculous Mycobacteria in Infants in Kenya
(a) Comparative clinical characteristics of those investigated for presumptive TB and infants with NTM isolated (categorical). |
| Clinical Characteristics | Presumptive TB | NTM +ve | OR (95%CI) | N (column %) | N (row%) | (n=742) | (n=19) |
| Any TB case (clinical or confirmed) | | | | No | 694 (94%) | 16 (2.3%) | 1 (ref) | Yes | 48 (6.5%) | 3 (6.3%) | 11.6 (3.25, 41.0) |
| MTBC +ve TB case | | | | No | 733 (99%) | 17 (2.3%) | 1 (ref) | Yes | 9 (1%) | 2 (22.2%) | 48.3 (9.34, 249) |
| Chest Radiograph | | | | Normal | 590 (80%) | 13 (2.2%) | 1(ref) | Abnormal not TB | 110 (15%) | 4 (3.6%) | 1.71 (0.55, 5.35) | Abnormal TB | 35 (5.0%) | 2 (5.7%) | 2.80 (0.61, 12.9) | missing | 7 (0.9%) | | |
| Keith Edward TB score | | | | <7 | 675 (90%) | 17 (2.5%) | 1 (ref) | >=7 | 32 (4.3%) | 2 (6.3%) | 2.62 (0.58, 11.9) | Missing | 35 (4.7%) | | |
| Reason for TB suspicion | | | | History of hospitalization | | | | No | 283 (38%) | 8 (3.4%) | 1 (ref) | Yes | 426 (57%) | 11(2.6%) | 0.78 (0.31, 1.97) | Missing | 33 (5.0%) | | |
| TB Contact History | | | | No | 579 (78%) | 13(2.3%) | 1 (ref) | Yes | 131 (18%) | 6 (4.6%) | 2.57 (0.96, 6.88) | Missing | 32 (4.0%) | | |
| TST results | | | | Negative | 555 (76%) | 14 (74%) | 1 (ref) | Positive | 172 (24%) | 5 (26%) | 1.15 (0.41, 3.25) |
| TB symptoms | | | | No | 530 (71%) | 15 (2.8%) | 1 (ref) | Yes | 180 (24%) | 4 (2.2%) | 0.85 (0.28, 2.58) | Missing | 32 (4.0%) | | |
| Nutritional Status at admission | | | | Healthy | 379 (51%) | 8 (2.1%) | 1 (ref) | At risk | 195 (27%) | 6 (3.0%) | 1.48 (0.51, 4.32) | Moderate Acute | 113 (15%) | 2 (1.8%) | 0.84 (0.18, 4.03) | Malnutrition (MAM) | | | | Severe Acute | 40 (5%) | 3 (7.5%) | 3.73 (0.95, 14.7) | Malnutrition (SAM) | | | | Missing | 15 (2%) | | |
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(b) Comparative clinical characteristics for those investigated for presumptive TB and infants with NTM isolated (continuous variable). |
| Clinical Characteristic | Categories | n | Mean age (95% CI) | Rank sum p- value/t-test p value |
| Mean age at TB investigation (months) | NTM negative Presumptive TB | 718 | 9.34 (8.95, 9.74) | 0.20 |
| | NTM case | 19 | 11.0 (8.02, 13.9) | |
| | Missing | 5 | | |
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