Acute Severe Anaphylaxis in Nepali Patients with Neurotoxic Snakebite Envenoming Treated with the VINS Polyvalent Antivenom

Table 2

Details of the clinical events in 13 neurotoxically envenomed patients with postantivenom serious adverse events.

Patient	NS D0	AVR	CR arrest	Shock	Hypotension	SB	Dyspnoea	Wheeze	Cyanosis	Cough	NS	Frothy secretions	P Resp	LO	VAP	Restless	Drowsy	Vomiting	Rash	Soft tissue oedema	Fever	Total	Outcome
13	2	H	1	-	-	-	-	-	-	-	2	1	-	-	1	1	-	1	1	-	-	8	D
12	2	H	2	-	-	2	1	-	-	-	-	-	-	-		1	1	-	1	-	-	8	D
11	2	L	-	-	-	-	1	-	-	-	-	-	-	1	-	-	-	-	1	1	-	4	D
10	2	H	1	1	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1	1	1	5	D
9	2	L	1	1	-	-	1	-	-	-	-	-	-	-	-	-	-	-	1	-	-	4	D
8	2	H	1	-	-	1	1	1	-	-	1	1	-	-	-	-	-	1	1	-	-	8	D
7	3	H	2	-	-	1	1		-	-		-	-	-	-	-	-	-	-	-	-	4	D
6	3	H	1	-	1	1	-	-	-	-	1	-	1	-	-	-	-	-	-	-	-	5	D
5	2	H	-	-	1	-	1	1	-	-	-	-	-	-	-	-	-	-	1	-	-	4	R
4	4	H	-	-	-	-	1	1	1	-	-	-	-	-	-	1	-	-	-	-	-	4	R
3	4	L	-	-	1	-	1	-	-	-	-	-	-	-	-	-	-	-	1	-	-	3	R
2	1	H	-	1	-	-	-	-	-	-	-	-	-	-	-	-	-	1	1	-	1	4	R
1	4	L	-	-	-	-	-	-	-	1	-	-	-	1	-	-	-	-	1	-	-	3	R
Total			9	3	3	5	8	3	1	1	4	2	1	2	1	3	1	3	10	2	2	64

NS D0: neurotoxicity score on Day 0 (baseline); AVR: antivenom regimen; H: high-dose antivenom regimen; L: low-dose antivenom regimen; CR: cardiorespiratory; SB: sinus bradycardia.
P Resp: paradoxical respiration; LO: laryngeal oedema; VAP: ventilator associated pneumonia; D: died; R: resolved.
: unilateral lower eyelid swelling.
: recorded as angioedema, exact anatomical location unknown.