Journal of Tropical Medicine

Immunity to Visceral Leishmaniasis


Publishing date
01 Oct 2011
Status
Published
Submission deadline
01 Apr 2011

Lead Editor

1Infectious Diseases and Immunology Division, Indian Institute of Chemical Biology, 4 Raja, S. C. Mullick Road, West Bengal, Kolkata 700 032, India

2Faculty of Medicine, Addis Ababa University, P.O. Box 28017, 1000 Addis Ababa, Ethiopia

3Departamento de Biología Molecular, Centro de Biología Molecular “Severo Ochoa” C/ Nicolás Cabrera, 1 Universidad Autónoma de Madrid, 28049 Madrid, Spain

4Australian Centre for Vaccine Development, Queensland Institute of Medical Research, 300 Herston Road, Herston, QLD 4006, Australia


Immunity to Visceral Leishmaniasis

Description

Visceral leishmaniasis (VL) or kala-azar caused by Leishmania donovani complex (i.e., L. donovani and L. infantum in Old World and L. chagasi in New World) is prevalent in 62 countries with an estimated occurrence of 0.5 million new cases annually. The absence of an effective vaccine, as well as safe and cost-effective antileishmanial agents, together with the emergence of resistant parasite strains and immunodeficiency virus (HIV) coinfection, have posed a serious challenge to the containment of the disease. Therefore, a better understanding of the host-parasite interactions and development of novel therapeutic and prophylactic modalities is needed for an effective control of VL.

We invite authors to submit original research and review articles that stimulate the ongoing effort to elucidate the complex immunological mechanism involved in pathogenesis, as well as in resistance to infection. We are interested in articles that explore aspects of antileishmanial immunity in humans, as well as in animal models. Manuscripts on immunochemotherapy, vaccination, and vaccine design are also welcome. Potential topics include, but are not limited to:

  • Host-parasite interactions and disease pathogenesis
  • Effects of sand fly saliva on Leishmania transmission and disease
  • Immune responses in kala-azar and PKDL
  • Development of vaccines against visceral leishmaniasis
  • Immunotherapy in visceral leishmaniasis
  • Immune responses in kala-azar patients with HIV coinfection
  • Identifying immune evasion mechanisms employed by parasites
  • Host cell signaling in visceral leishmaniasis
  • Leishmania-induced alteration of host cell antigen presentation
  • New cellular and animal models to understand immunity to parasites
  • Molecules/antigens of Leishmania with serodiagnostic potential in visceral leishmaniasis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jtm/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 780809
  • - Editorial

Immunity to Visceral Leishmaniasis

Nahid Ali | Asrat Hailu Mekuria | ... | Christian Engwerda
  • Special Issue
  • - Volume 2012
  • - Article ID 819512
  • - Review Article

Host Cell Signalling and Leishmania Mechanisms of Evasion

Marina Tiemi Shio | Kasra Hassani | ... | Martin Olivier
  • Special Issue
  • - Volume 2012
  • - Article ID 650874
  • - Review Article

Adenosine and Immune Imbalance in Visceral Leishmaniasis: The Possible Role of Ectonucleotidases

Rafael Paletta-Silva | José Roberto Meyer-Fernandes
  • Special Issue
  • - Volume 2012
  • - Article ID 631460
  • - Review Article

Immunity to Visceral Leishmaniasis Using Genetically Defined Live-Attenuated Parasites

Angamuthu Selvapandiyan | Ranadhir Dey | ... | Hira L. Nakhasi
  • Special Issue
  • - Volume 2012
  • - Article ID 892817
  • - Review Article

Development of Vaccines against Visceral Leishmaniasis

Krystal J. Evans | Lukasz Kedzierski
  • Special Issue
  • - Volume 2012
  • - Article ID 541571
  • - Review Article

Cytokine and Phenotypic Cell Profiles of Leishmania infantum Infection in the Dog

Carla Maia | Lenea Campino
  • Special Issue
  • - Volume 2012
  • - Article ID 639304
  • - Review Article

Differential Regulation of the Immune Response in the Spleen and Liver of Mice Infected with Leishmania donovani

Rashmi Bankoti | Simona Stäger
Journal of Tropical Medicine
 Journal metrics
Acceptance rate40%
Submission to final decision68 days
Acceptance to publication32 days
CiteScore2.500
Impact Factor1.233
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