Convulsive and Neurodegenerative Effects in Rats of Some Isolated Toxins from the Tityus bahiensis Scorpion Venom

Table 1

Behavioral effects of injection of Tityus bahiensis scorpion venom toxins into the hippocampus. The rats had cannulae and electrodes implanted in the CA1 area of the hippocampus. The observations were made up to 4 h after injection.

	Yawning	Orofacial automatisms	Increased salivary and/or nasal secretions	Myoclonus	Wet dog shakes (WDS)
Ringer (𝑛=8)	—	—	—	—	—
Tb V-1 (𝑛=12)	83.33%*	83.33%*	41.6%	100%*	83.33%*
Tb V-5 (𝑛=13)	92.31%*	76.92%*	—	84.46%*	61.54%*
Tb V-24 (𝑛=8)	50%*	33.33%	16.6%	83.33%*	50%*
Tb V-27 (𝑛=8)	25%	37.5%	37.5%	37.5%	50%*
Tb V-28 (𝑛=8)	12.5%	62.5%*	—	75%*	62.5%*

∗Significantly different from control group treated with Ringer solution; 𝑃<0.05, Fisher’s exact test.