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Journal of Thyroid Research
Volume 2010, Article ID 101948, 5 pages
http://dx.doi.org/10.4061/2010/101948
Research Article

Increasing Incidence, but Lack of Seasonality, of Elevated TSH Levels, on Newborn Screening, in the North of England

1Institute of Health and Society, Newcastle University, Newcastle upon Tyne NE1 4LP, UK
2Department of Paediatrics, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
3Department of Biochemistry, University Hospital of North Durham, Durham DH1 5TW, UK
4Department of Clinical Biochemistry, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
5Department of Microbiology, University Hospital of North Durham, Durham DH1 5TW, UK
6Department of Paediatrics, James Cook University Hospital, Middlesbrough TS3 3TA, UK

Received 3 June 2009; Accepted 15 December 2009

Academic Editor: Jack R. Wall

Copyright © 2010 Mark S. Pearce et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. Van Vliet, “Development of the thyroid gland: lessons from congenitally hypothyroid mice and men,” Clinical Genetics, vol. 63, no. 6, pp. 445–455, 2003. View at Publisher · View at Google Scholar
  2. K. B. Harris and K. A. Pass, “Increase in congenital hypothyroidism in New York State and in the United States,” Molecular Genetics and Metabolism, vol. 91, no. 3, pp. 268–277, 2007. View at Publisher · View at Google Scholar · View at PubMed
  3. M. E. Rendón-Macías, I. Morales-García, E. Huerta-Hernández, A. Silva-Batalla, and M. A. Villasís-Keever, “Birth prevalence of congenital hypothyroidism in Mexico,” Paediatric and Perinatal Epidemiology, vol. 22, no. 5, pp. 478–485, 2008. View at Publisher · View at Google Scholar · View at PubMed
  4. J. Deladoëy, N. Bélanger, and G. Van Vliet, “Random variability in congenital hypothyroidism from thyroid dysgenesis over 16 years in Québec,” Journal of Clinical Endocrinology and Metabolism, vol. 92, no. 8, pp. 3158–3161, 2007. View at Publisher · View at Google Scholar · View at PubMed
  5. S. K. Hall, A. C. J. Hutchesson, and J. M. Kirk, “Congenital hypothyroidism, seasonality and consanguinity in the West Midlands, England,” Acta Paediatrica, vol. 88, no. 2, pp. 212–215, 1999. View at Publisher · View at Google Scholar
  6. G. P. Leese, R. V. Flynn, R. T. Jung, T. M. MacDonald, M. J. Murphy, and A. D. Morris, “Increasing prevalence and incidence of thyroid disease in Tayside, Scotland: the Thyroid Epidemiology Audit and Research Study (TEARS),” Clinical Endocrinology, vol. 68, no. 2, pp. 311–316, 2008. View at Publisher · View at Google Scholar · View at PubMed
  7. I. Hunter, S. A. Greene, T. M. MacDonald, and A. D. Morris, “Prevalence and aetiology of hypothyroidism in the young,” Archives of Disease in Childhood, vol. 83, no. 3, pp. 207–210, 2000. View at Publisher · View at Google Scholar
  8. M. Virtanen, J. Mäenpää, J. Pikkrainen, L. Pitkänen, and J. Perheentupa, “Aetiology of congenital hypothyroidism in Finland,” Acta Paediatrica Scandinavica, vol. 78, no. 1, pp. 67–73, 1989. View at Google Scholar
  9. K. Miyai, J. F. Connelly, T. P. Foley Jr. et al., “An analysis of the variation of incidence of congenital dysgenetic hypothyroidism in various countries,” Endocrinologia Japonica, vol. 31, no. 1, pp. 77–81, 1984. View at Google Scholar
  10. M. Nakamizo, S.-I. Toyabe, T. Asami, and K. Akazawa, “Seasonality in the incidence of congenital hypothyroidism in Japan,” Journal of Paediatrics and Child Health, vol. 41, no. 7, pp. 390–391, 2005. View at Publisher · View at Google Scholar
  11. K. Miyai, K. Inaoka, T. Miyagi et al., “Further studies on episodic occurrence of congenital dysgenetic hypothyroidism in Osaka, Japan,” Endocrine Journal, vol. 52, no. 5, pp. 599–603, 2005. View at Publisher · View at Google Scholar
  12. M. Rosenthal, G. M. Addison, and D. A. Price, “Congenital hypothyroidism: increased incidence in Asian families,” Archives of Disease in Childhood, vol. 63, no. 7, pp. 790–793, 1988. View at Google Scholar
  13. S. A. Reijneveld and P. H. Verkerk, “No evidence for seasonality of congenital hypothyroidism in The Netherlands,” Acta Paediatrica, vol. 82, no. 2, pp. 212–213, 1993. View at Google Scholar
  14. G. Henry, S. H. Sobki, and J. M. Othman, “Screening for congenital hypothyroidism,” Saudi Medical Journal, vol. 23, no. 5, pp. 529–535, 2002. View at Google Scholar
  15. Department of Health and Social Security (DHSS), “Screening for early detection of congenital hypothyroidism,” Tech. Rep. HN(81)20, DHSS, London, UK, 1981. View at Google Scholar
  16. J. H. Jones, J. Mackenzie, G. A. Croft, S. Beaton, D. Young, and M. Donaldson, “Improvement in screening performance and diagnosis of congenital hypothyroidism in Scotland 1979–2003,” Archives of Disease in Childhood, vol. 91, no. 8, pp. 680–685, 2006. View at Publisher · View at Google Scholar · View at PubMed
  17. S. F. Ahmed, N. D. Barnes, and I. A. Hughes, “Initial evaluation of congenital hypothyroidism: a survey of general paediatricians in East Anglia,” Archives of Disease in Childhood, vol. 77, no. 4, pp. 339–341, 1997. View at Google Scholar
  18. R. J. Perry, S. Maroo, A. C. Maclennan, J. H. Jones, and M. D. C. Donaldson, “Combined ultrasound and isotope scanning is more informative in the diagnosis of congenital hypothyroidism than single scanning,” Archives of Disease in Childhood, vol. 91, no. 12, pp. 972–976, 2006. View at Publisher · View at Google Scholar · View at PubMed
  19. J. H. Oppenheimer, L. E. Braverman, A. Toft, I. M. Jackson, and P. W. Ladenson, “A therapeutic controversy: thyroid hormone treatment: when and what?” Journal of Clinical Endocrinology and Metabolism, vol. 80, no. 10, pp. 2873–2883, 1995. View at Google Scholar
  20. J. H. Edwards, “The recognition and estimation of cyclic trends,” Annals of Human Genetics, vol. 25, pp. 83–87, 1961. View at Google Scholar
  21. G. Vassart and J. E. Dumont, “Thyroid dysgenesis: multigenic or epigenetic . . . or both?” Endocrinology, vol. 146, no. 12, pp. 5035–5037, 2005. View at Publisher · View at Google Scholar · View at PubMed
  22. K. B. Harris and K. A. Pass, “Increase in congenital hypothyroidism in New York State and in the United States,” Molecular Genetics and Metabolism, vol. 91, no. 3, pp. 268–277, 2007. View at Publisher · View at Google Scholar · View at PubMed
  23. F. Calaciura, R. M. Motta, G. Miscio et al., “Subclinical hypothyroidism in early childhood: a frequent outcome of transient neonatal hyperthyrotropinemia,” Journal of Clinical Endocrinology and Metabolism, vol. 87, no. 7, pp. 3209–3214, 2002. View at Publisher · View at Google Scholar
  24. A. L. Daliva, B. Linder, J. DiMartino-Nardi, and P. Saenger, “Three-year follow-up of borderline congenital hypothyroidism,” Journal of Pediatrics, vol. 136, no. 1, pp. 53–56, 2000. View at Google Scholar
  25. C. Corbetta, G. Weber, F. Cortinovis et al., “A 7-year experience with low blood TSH cutoff levels for neonatal screening reveals an unsuspected frequency of congenital hypothyroidism (CH),” Clinical Endocrinology, vol. 71, no. 5, pp. 739–745, 2009. View at Publisher · View at Google Scholar · View at PubMed
  26. Office for National Statistics, in Social Focus in Brief: Ethnicity, Office for National Statistics, London, UK, 2002.
  27. S. Nishiyama, T. Mikeda, T. Okada, K. Nakamura, T. Kotani, and A. Hishinuma, “Transient hypothyroidism or persistent hyperthyrotropinemia in neonates born to mothers with excessive iodine intake,” Thyroid, vol. 14, no. 12, pp. 1077–1083, 2004. View at Publisher · View at Google Scholar · View at PubMed
  28. M. Korada, M. S. Pearce, E. Avis, S. Turner, and T. Cheetham, “TSH levels in relation to gestation, birth weight and sex,” Hormone Research, vol. 72, no. 2, pp. 120–123, 2009. View at Publisher · View at Google Scholar · View at PubMed
  29. S. M. Miller, M. L. Green, J. V. Depinto, and K. C. Hornbuckle, “Results from the Lake Michigan Mass Balance study: concentrations and fluxes of atmospheric polychlorinated biphenyls and trans-nonachlor,” Environmental Science and Technology, vol. 35, no. 2, pp. 278–285, 2001. View at Publisher · View at Google Scholar
  30. M. S. Kibirige, S. Hutchison, C. J. Owen, and H. T. Delves, “Prevalence of maternal dietary iodine insufficiency in the north east of England: implications for the fetus,” Archives of Disease in Childhood, vol. 89, no. 5, pp. F436–F439, 2004. View at Publisher · View at Google Scholar · View at PubMed
  31. Y.-H. Gu, T. Kato, S. Harada, H. Inomata, T. Saito, and K. Aoki, “Seasonality in the incidence of congenital hypothyroidism in Japan: gender-specific patterns and correlation with temperature,” Thyroid, vol. 17, no. 9, pp. 869–874, 2007. View at Publisher · View at Google Scholar · View at PubMed