Alterations along the Hypothalamic-Pituitary-Thyroid Axis of the Zebrafish (Danio rerio) after Exposure to Propylthiouracil
Figure 13
Representative ultrastructural alterations in hepatocytes of control (a) and PTU-exposed zebrafish (b). In the control fish, glycogen storage deposits are clearly visible ((a): *), whereas the exposed fish hardly display any glycogen in the cytoplasm. Moderate reductions and fenestrations of the rough endoplasmic reticulum are observable in PTU-exposed zebrafish ((b): ▲). Furthermore, the number of mitochondria is decreased. Magnification: 10,000x.
