Clinical Study

Pattern and Risk Factors of Central Compartment Lymph Node Metastasis in Papillary Thyroid Cancer: A Prospective Study from an Endocrine Surgery Centre

Table 3

Univariate analysis of central compartment lymph nodes metastasis (CCM), ipsilateral CCM and contralateral CCM with known risk factors.

CCMIpsilateral CCMContralateral CCM
Present 𝑛 = 2 8 Absent 𝑛 = 1 9 𝑃 valuePresent 𝑛 = 2 6 Absent 𝑛 = 2 1 𝑃 valuePresent 𝑛 = 1 9 Absent 𝑛 = 2 8 𝑃 value

Age (years)34.96 ± 14.4137 ± 9.740.59434.42 ± 14.8337.48 ± 9.380.41034.68 ± 15.7736.67 ± 11.030.602
Age group
 ≤45 years24161.00022181.00016230.928
 >45 years434334
Sex
Male970.7637690.355780.608
Female191219121219
Tumor size (cm)4.2 ± 2.452.58 ± 2.020.018*4.4 ± 2.42.5 ± 2.00.013*4.02 ± 2.233.38 ± 2.50.378
Tumor staging
 T1221321
 T28110.3268110.7605140.324
 T3838356
 T41039476
Tumor subtype
 Classical variant221320151420
 Follicular variant350.580350.619260.434
 Oncocytic variant101010
 Tall cell variant212121
Multicentricity1350.1691260.2451250.002*
Bilaterality630.631541.000630.085
Extrathyroidal extension1030.1441030.102750.170
Ipsilateral CCM1790.001*