Review Article

New Genetic Insights from Autoimmune Thyroid Disease

Table 3

Genes linked and/or associated with autoimmune thyroid disease.

Gene symbolGene nameChromosome locationOdds ratio

HLAMajor histocompatibility complex6p212.0–4.0
CTLA4Cytotoxic T-lymphocyte-associated protein 42q331.5–2.2
PTPN22Protein tyrosine phosphatase, non-receptor type 22 (lymphoid)1p131.4–1.9
CD40CD40 molecule, TNF receptor superfamily member 520q111.3–1.8
IL2RA (CD25)Interleukin 2 receptor, alpha10p151.1–1.4
FCRL3Fc receptor-like 31q231.1–1.3
TGThyroglobulin8q241.3–1.6
TSHRThyroid-stimulating hormone receptor14q311.4–2.6