Atypical Clinical Manifestations of Graves' Disease: An Analysis in Depth

Table 1

Manifestations of Graves’ disease (GD).

Well recognized/common	Recognized/Less common	Unusual/atypical (estimated prevalence in GD patients)
Weight loss	Agitation/psychosis	Jaundice (mild hyperbilirubinemia in up to 30%)
Anxiety/nervousness	Apathy/depression	Vomiting (up to 44%)
Tremors	Confusion/delirium	Anemia (up to 33%)
Goiter	Myopathy	Pancytopenia
Tachyarrhythmia	Paraparesis or quadriparesis	Leukopenia/thrombocytopenia
Breathlessness	Abnormal liver function tests	Heart block
Left ventricular failure		Myocardial infarction
Increased bowel movements		Pulmonary hypertension (up to 43%)
Sweating		Right heart failure
Heat intolerance		Angioedema
Staring gaze/exophthalmos		Erythema annulare centrifugum