Review Article
Prognostic Factors of Papillary and Follicular Carcinomas in Japan Based on Data of Kuma Hospital
Table 2
Risk classification of TPC based on preoperative, intraoperative, and pathological findings.
| High risk | (a) Patients having distant metastasis at presentation. | (b) Patients including PDC components in majority of carcinoma lesions. | (c) Patients diagnosed as tall cell variant. | (d) Patients 55 yrs or older and having one of the following three: | (1) tumor size >2 cm with extension to adjacent organs, (corresponding to T4), | (2) lymph-node metastasis >3 cm, | (3) lymph-node metastasis extending to adjacent organs |
| Intermediate risk | (a) Patients including PDC component in small portion of carcinoma lesions. | (b) Patients 55 yrs or older and having one of the following three: | (1) tumor size >4 cm (excluding T4 cases), | (2) tumor size ≤2 cm with extension to adjacent organs (corresponding to T4), | (3) lymph-node metastasis detectable on preoperative imaging studies ≤3 cm and without extension to adjacent organs |
| Low risk | (a) Patients under 55 yrs without distant metastasis at diagnosis. | (b) Patients 55 yrs or older who are not classified as high risk or intermediate risk |
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