Prognostic Factors of Papillary and Follicular Carcinomas in Japan Based on Data of Kuma Hospital

Table 2

Risk classification of TPC based on preoperative, intraoperative, and pathological findings.

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High risk

 (a) Patients having distant metastasis at presentation.

 (b) Patients including PDC components in majority of carcinoma lesions.

 (c) Patients diagnosed as tall cell variant.

 (d) Patients 55 yrs or older and having one of the following three:

   (1) tumor size >2 cm with extension to adjacent organs, (corresponding to T4),

  (2) lymph-node metastasis >3 cm,

  (3) lymph-node metastasis extending to adjacent organs

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Intermediate risk

 (a) Patients including PDC component in small portion of carcinoma lesions.

 (b) Patients 55 yrs or older and having one of the following three:

  (1) tumor size >4 cm (excluding T4 cases),

  (2) tumor size ≤2 cm with extension to adjacent organs (corresponding to T4),

  (3) lymph-node metastasis detectable on preoperative imaging studies ≤3 cm and without extension to adjacent organs

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Low risk

 (a) Patients under 55 yrs without distant metastasis at diagnosis.

 (b) Patients 55 yrs or older who are not classified as high risk or intermediate risk

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