TY - JOUR
A2 - Pantos, Constantinos
AU - Safer, Joshua D.
PY - 2013
DA - 2013/03/20
TI - Thyroid Hormone and Wound Healing
SP - 124538
VL - 2013
AB - Although thyroid hormone is one of the most potent stimulators of growth and metabolic rate, the potential to use thyroid hormone to treat cutaneous pathology has never been subject to rigorous investigation. A number of investigators have demonstrated intriguing therapeutic potential for topical thyroid hormone. Topical T3 has accelerated wound healing and hair growth in rodents. Topical T4 has been used to treat xerosis in humans. It is clear that the use of thyroid hormone to treat cutaneous pathology may be of large consequence and merits further study. This is a review of the literature regarding thyroid hormone action on skin along with skin manifestations of thyroid disease. The paper is intended to provide a context for recent findings of direct thyroid hormone action on cutaneous cells in vitro and in vivo which may portend the use of thyroid hormone to promote wound healing.
SN - 2090-8067
UR - https://doi.org/10.1155/2013/124538
DO - 10.1155/2013/124538
JF - Journal of Thyroid Research
PB - Hindawi Publishing Corporation
KW -
ER -