Serum Resistin and Insulin-Like Growth Factor-1 Levels in Patients with Hypothyroidism and Hyperthyroidism

Table 1

Comparisons of laboratory findings and demographic characteristics of total HT, total HrT, and healthy control groups.

Parameters	Reference ranges	Total hypothyroid group (𝑛=31); Mean ± SD; Median; (min-max)	Total hyperthyroid group (𝑛=30); Mean ± SD; Median; (min-max)	Control group (𝑛=17); Mean ± SD; Median; (min-max)
Age (year)	(—)	47.84 ± 13.31*	43.43 ± 15.66; 39.5 (22–79)	37 ± 12.53; 34 (22–72)
T-Chol (mg/dL)	120–200	235.13 ± 56.99^*†	162.57 ± 42.04	178.41 ± 31.64
HDL-Chol (mg/dL)	35–70	56.61 ± 13.39	52.17 ± 11.61	59.65 ± 14.11
LDL-Kol (mg/dL)	<130	144.19 ± 48.6^*†	89.9 ± 32.32	100.24 ± 26.88
AST (U/L)	0–50	41.58 ± 46.12^‡; 24 (16–213)	23.43 ± 7.72	19.06 ± 4.46; 18 (15–34)
ALT (U/L)	0–50	43.68 ± 58.49; 21 (5–265)	24.47 ± 10.18	19.12 ± 9.76; 17 (7–50)
TSH (µIU/mL)	0.34–5.6	50.85 ± 75.03^*†; 15.74 (5.63–306.3)	0.089 ± 0.090^α; 0.04 (0.015–0.279)	2.10 ± 1.26
fT4 (ng/dL)	0.58–1.64	0.53 ± 0.23*	2.08 ± 1.20^†α; 1.68 (0.68–4.85)	0.83 ± 0.10; 0.81 (0.73–1.03)
Resistin (ng/mL)	(—)	12.66 ± 6.04^∞; 11.98 (5.28–30.32)	12.19 ± 7.13; 11.1 (3.84–33.5)	8.45 ± 2.90
IGF-I (ng/mL)	64–345	117.22 ± 52.03^†*; 104 (58.8–241)	155.17 ± 51.67	184 ± 49.73

 𝑃<0.05; *: hypothyroid and control; ^†: hypothyroid and hyperthyroid; ^α: hyperthyroid and control.
 ^‡𝑃=0.002 (hypothyroid and control); ^∞𝑃=0.025 (hypothyroid and control).