Journal of Thyroid Research / 2013 / Article / Fig 8

Research Article

Mechanisms of L-Triiodothyronine-Induced Inhibition of Synaptosomal Na+-K+-ATPase Activity in Young Adult Rat Brain Cerebral Cortex

Figure 8

Modulation of the T3 action on synaptosomal Na+-K+-ATPase activity by sodium orthovanadate. A higher dose of T3 (10 nM) was chosen from the T3 dose-response curve considering its greater inhibitory action on the Na+-K+-ATPase activity and to observe the effect of graded doses (1 nM–2 mM) of sodium orthovanadate on this T3-induced inhibition. The data are represented as mean ± SEM of four separate experiments, taking six animals in each group. The vertical bars denote SEM. Open circles indicate mean values for a set of control incubations without T3. Filled triangles indicate the results of a set of incubations with 10 nM T3.

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