Parathyroid Gland Involvement by Thyroid Cancer: Results from a Large Series of Thyroidectomies Performed in Two Italian University Hospitals and Review of the Literature
Table 1
Personal and histological characteristics of the 10 patients recruited in the present study.
Patient 1
Patient 2
Patient 3
Patient 4
Patient 5
Patient 6
Patient 7
Patient 8
Patient 9
Patient 10
Sex
F
M
F
F
F
F
M
F
F
M
Age (yrs)
58
44
54
76
34
38
66
65
68
47
Primary tumor histotype
FVPTC
Tall cell PTC
Classic PTC
Classic PTC
FVPTC
Classic PTC
Classic PTC
FVPTC
Classic PTC
Classic PTC
Primary tumor size (cm)
1.5
3.3
1.6
2.3
3
2.3
1.9
2.8
3.2
2.5
Extrathyroid invasion of tissues other than parathyroid
No
Yes
No
Yes
No
Yes
No
Yes
Yes
Yes
Lymph node metastases
Yes
Yes
No
No
No
Yes
No
No
No
No
Distant metastases
No
No
No
No
No
No
No
No
No
No
Patterns of parathyroid involvement
Pattern B
Pattern A
Pattern A + B
Pattern A
Pattern A
Pattern A + B
Pattern A
Pattern A
Pattern A
Pattern A + B
Stage*
III (pT3N1aM0)
I (pT3N1aM0)
III (pT3N0M0)
III (pT3N0M0)
I (pT3N0M0)
I (pT3N1aM0)
III (pT3N0M0)
III (pT3N0M0)
III (pT3N0M0)
III (pT3N0M0)
Recurrence
No
No
No
No
No
No
No
No
No
No
Follow-up time (yrs)
3
10
6
4
5
2
9
8
1
7
FVPTC: follicular variant of papillary thyroid carcinoma; PTC: papillary thyroid carcinoma; Pattern B: extension of thyroid malignancy into the parathyroid, in which cancer nests are separated from by a pseudocapsule; Pattern C: true thyroid cancer metastasis within the parathyroid, with no evidence of continuity from the primary thyroid tumor. *Based on AJCC/International Union against Cancer (AJCC/UICC) classification system [11].
