Research Article

Significance of TNF-α and the Adhesion Molecules: L-Selectin and VCAM-1 in Papillary Thyroid Carcinoma

Table 8

Univariate survival analysis for OS in PTC patients ().

Variables Patients diedLog rank test statistics
(%)

Age
45 years37 1 (3) Log rank = 4.472, df = 1,
45 years 39 7 (18)
Gender
 Female 51 2 (4) Log rank = 6.870, df = 1,
 Male 25 6 (24)
Metastasis
 Absent 67 5 (7) Log rank = 7.581, df = 1,
 Present 9 3 (33)
Stage
 Early (I + II) 43 1 (2) Log rank = 6.859, df = 1,
 Advanced (III + IV) 33 7 (21)
Multifocality
 Absent 59 4 (7) Log rank = 4.130, df = 1,
 Present 17 4 (23)

Circulating levels
Circulating TNF-α
 Low381 (3)Log rank = 5.129, df = 1,
 High387 (18)
Circulating L-Selectin
 Low385 (13)Log rank = 0.502, df = 1,
 High383 (8)
Circulating VCAM-1
 Low383 (8)Log rank = 0.515, df = 1,
 High385 (13)

Tumoural protein expression
TNF-α expression
 Low44 5 (11) Log rank = 0.059, df = 1,
 High32 3 (91)
L-Selectin expression
 Low46 7 (15) Log rank = 2.697, df = 1,
 High30 1 (7)
VCAM-1 expression
 Low46 5 (11) Log rank = 0.027, df = 1,
 High30 3 (10)