Research Article
Change in Practice over Four Decades in the Management of Graves’ Disease in Scotland
Table 1
Demographic characteristics and index therapy according to decades.
| | | Whole study
1968–2007 | Group A
1968–1977 | Group B
1978–1987 | Group C
1988–1997 | Group D
1998–2007 |
| | Total number of GT patients (%) | 3737 (100%) | 436 (11.7%) | 755 (20.2%) | 1185 (31.7%) | 1361 (36.4%) | | Gender distribution | | | | | | | Females (%) | 3155 (84.4%) | 381 (87.4%) | 642 (85%) | 1000 (84.4%) | 1132 (83.2%) | | Males (%) | 582 (15.6%) | 55 (12.6%) | 113 (15%) | 185 (15.6%) | 229 (16.8%) | | Female : male | 5.4 : 1 | 6.9 : 1 | 5.7 : 1 | 5.4 : 1 | 4.9 : 1 | Overall age
Mean ± std dev | | | | | | Age of females
Mean ± std dev | | | | | | Age of males
Mean ± std dev | | | | | | | Index treatment used | | | | | | | Antithyroid drugs | 320 (8.6%) | 27 (6.2%) | 47 (6.2%) | 76 (6.4%) | 170 (12.5%) | | Radioactive iodine | 2274 (60.1%) | 157 (36%) | 371 (49.1%) | 830 (70%) | 916 (67.3%) | | Surgery | 873 (23.4%) | 210 (48.2%) | 293 (38.8%) | 212 (17.9%) | 158 (11.6%) | | Surgery + RAI | 87 (2.3%) | 31 (7.1%) | 28 (3.7%) | 18 (1.5%) | 10 (0.7%) |
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GT: Graves’ thyrotoxicosis; std dev: standard deviation; RAI: radioactive iodine.
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