¹⁸F-FDG Pet-Guided External Beam Radiotherapy in Iodine-Refractory Differentiated Thyroid Cancer: A Pilot Study

Table 2

Treatments history.

Case	Surgical; interventions at diagnosis	Other surgical; interventions	N° RAI; (total dose MBq)	Range primary; diagnosis,; EBRT (months)	Tg on L-T4 therapy at last recurrence (ng/ml)	Stimulated Tg at last recurrence  (ng/ml)
1	TT + neck LA (central + ipsilateral)	Bilateral clavicular LA	3 (11100)	61	18.3	530.0
2	TT + neck LA (central)	Surgical neck LA (central) revision	2 (11100)	96	<0.	<0.
3	TT + neck LA (central + ipsilateral)	—	1 (5624)	3	1.1	41.5
4	TT + neck LA (central)	Bilateral neck LA	5 (18500)	72	5.6	294.0
5	TT + neck LA (ipsilateral)	Contralateral neck LA	3 (18620)	22	2.5	14.3
6	TT + neck LA (ipsilateral)	Ipsilateral paratracheal LA	3 (12921)	103	3.1	18.3
7	TT + neck LA (central)	—	1 (5534)	6	21.9	74.4
8	TT	Ipsilateral clavicular LA	4 (25900)	154	17.8	25.8
9	TT + neck LA (central)	—	2 (9425)	49	1.0	1.5
10	TT	—	1 (5533)	2	299.0	706.0
11	TT + neck LA (ipsilateral)	—	2 (11163)	25	3.3	19.1
12	TT + neck LA (bilateral) + partial laryngectomy	Surgical unilateral neck LA revision	3 (11290)	82	4.7	184.0
13	TT + neck LA (bilateral)	—	3 (18620)	95	114.0	388.0
14	TT + neck LA (central)	Mediastinal LA + contralateral neck LA	2 (9284)	20	3.2	27.8
15	TT + neck LA sampling (central)	—	1 (7322)	2	3.5	102.0
16	TT + neck LA (bilateral) + laryngectomy	—	1 (5714)	3	80.0	167.0

of high AbTg levels; EBRT: external beam radiotherapy; Tg: thyroglobulin; LA: lymphadenectomy; RAI: radioiodine ablation; TT: total thyroidectomy; WBS: whole body scintigraphy.