Research Article

Microscopic Positive Tumor Margin Increases Risk for Disease Persistence but Not Recurrence in Patients with Stage T1-T2 Differentiated Thyroid Cancer

Table 3

RAI treatment: positive versus clear margins.

All patients n = 963Positive margins n = 112Clear margins n = 851 value

Initial RAI ablation
 Received RAI761 (79%)103 (92%)658 (77%)<0.001
 RAI dose (GBq)3.7 (1.1–7.4)3.7 (1.8–5.5)3.7 (1.1–7.4)

T1 patients (n = 603)
 Received RAI421 (70%)50 (86%)371 (68%)0.004
 RAI dose (GBq)3.7 (1.1–5.7)3.7 (1.8–5.5)3.7 (1.1–5.7)

T2 patients (n = 360)
 Received RAI340 (94%)53 (98%)287 (93%)0.180
 RAI dose (GBq)3.7 (1.1–7.4)3.7 (3.7–5.5)3.7 (1.1–7.4)

Data are presented as number (percentage) or median (range). Positive versus clear margins. Patient was treated with RAI in 1996, unexplained high dose. for comparison with fraction of patients receiving RAI in T1 patients.