Microscopic Positive Tumor Margin Increases Risk for Disease Persistence but Not Recurrence in Patients with Stage T1-T2 Differentiated Thyroid Cancer

Table 5

Multivariate analysis of factors affecting disease persistence.

Risk factor	Hazard ratio (95% CI)	value
Sex (men)	0.344 (0.092–1.288)	0.113
Age at diagnosis	0.984 (0.953–1.015)	0.306
T staging	0.984 (0.432–2.242)	0.969
Nx/0	Referent
N1a	5.728 (2.274–14.424)	0.001
N1b	25.977 (9.412–71.696)	0.001
Follicular histology	0.000	0.998
Positive margins	2.952 (1.225–7.111)	0.016

Note. T1 is the referent for T2 and Nx/0 is the referent for N1a and N1b, papillary histology is the referent for follicular thyroid cancer, women was the referent for men, and clear margins were the referent for positive margins.